| 46261 | April 21 | Death | 1996 – Zora Arkus-Duntov, Belgian-born American engineer and racing driver (b. 1909) |
| 46262 | April 21 | Death | 1996 – Dzhokhar Dudayev, Chechen general and politician, 1st President of Ichkeria (b. 1944) |
| 46263 | April 21 | Death | 1996 – Abdul Hafeez Kardar, Pakistani cricketer (b. 1925) |
| 46264 | April 21 | Death | 1996 – Jimmy Snyder, American sportscaster (b. 1919) |
| 46265 | April 21 | Death | 1998 – Jean-François Lyotard, French sociologist and philosopher (b. 1924) |
| 46266 | April 21 | Death | 1999 – Buddy Rogers, American actor and singer (b. 1904) |
| 46267 | April 21 | Death | 2000 – Neal Matthews, Jr., American singer (The Jordanaires) (b. 1929) |
| 46268 | April 21 | Death | 2003 – Nina Simone, American singer-songwriter, pianist, and activist (b. 1933) |
| 46269 | April 21 | Death | 2004 – Mary McGrory, American journalist (b. 1918) |
| 46270 | April 21 | Death | 2005 – Gerry Marshall, English race car driver and journalist (b. 1941) |
| 46271 | April 21 | Death | 2006 – Johnny Checketts, New Zealand commander and pilot (b. 1912) |
| 46272 | April 21 | Death | 2006 – T. K. Ramakrishnan, Indian politician (b. 1922) |
| 46273 | April 21 | Death | 2006 – Telê Santana, Brazilian footballer and manager (b. 1931) |
| 46274 | April 21 | Death | 2007 – Lobby Loyde, Australian guitarist, songwriter, and producer (Purple Hearts, Wild Cherries, and Rose Tattoo) (b. 1941) |
| 46275 | April 21 | Death | 2010 – Mr. Hito, Japanese wrestler and trainer (b. 1942) |
| 46276 | April 21 | Death | 2010 – Gustav Lorentzen, Norwegian singer-songwriter and guitarist (Knutsen & Ludvigsen) (b. 1947) |
| 46277 | April 21 | Death | 2010 – Juan Antonio Samaranch, Spanish businessman (b. 1920) |
| 46278 | April 21 | Death | 2010 – Kanagaratnam Sriskandan, Sri Lankan-English engineer and civil servant (b. 1930) |
| 46279 | April 21 | Death | 2011 – Catharina Halkes, Dutch theologian and academic (b. 1920) |
| 46280 | April 21 | Death | 2012 – Doris Betts, American author and academic (b. 1932) |
| 46281 | April 21 | Death | 2012 – Charles Colson, American lawyer and activist, founded Prison Fellowship (b. 1931) |
| 46282 | April 21 | Death | 2012 – Albert Falco, French captain and diver (b. 1927) |
| 46283 | April 21 | Death | 2012 – Charles Higham, English-American author and poet (b. 1931) |
| 46284 | April 21 | Death | 2012 – Peter Milano, American mobster (b. 1925) |
| 46285 | April 21 | Death | 2012 – Jerry Toppazzini, Canadian ice hockey player and coach (b. 1931) |
| 46286 | April 21 | Death | 2013 – Kriyananda, Romanian-American spiritual leader (b. 1926) |
| 46287 | April 21 | Death | 2013 – Chrissy Amphlett, Australian singer-songwriter and actress (Divinyls) (b. 1959) |
| 46288 | April 21 | Death | 2013 – Shakuntala Devi, Indian mathematician and astrologer (b. 1929) |
| 46289 | April 21 | Death | 2013 – Leopold Engleitner, Austrian holocaust survivor, author, and educator (b. 1905) |
| 46290 | April 21 | Death | 2013 – Gordon D. Gayle, American general and historian (b. 1917) |