| 46561 | April 22 | Birth | 1978 – Paul Malakwen Kosgei, Kenyan runner and coach |
| 46562 | April 22 | Birth | 1978 – David Masters, English cricketer |
| 46563 | April 22 | Birth | 1978 – Matt Orford, Australian rugby player |
| 46564 | April 22 | Birth | 1978 – Jason Stollsteimer, American singer-songwriter and guitarist (The Von Bondies and Hounds Below) |
| 46565 | April 22 | Birth | 1978 – Esteban Tuero, Argentinian race car driver |
| 46566 | April 22 | Birth | 1979 – Zoltán Gera, Hungarian footballer |
| 46567 | April 22 | Birth | 1979 – Daniel Johns, Australian singer-songwriter and guitarist (Silverchair and The Dissociatives) |
| 46568 | April 22 | Birth | 1980 – Igor Budan, Croatian footballer |
| 46569 | April 22 | Birth | 1980 – Clarke Dermody, New Zealand rugby player |
| 46570 | April 22 | Birth | 1980 – Nicolas Douchez, French footballer |
| 46571 | April 22 | Birth | 1980 – Courtney Friel, American journalist |
| 46572 | April 22 | Birth | 1980 – Carlos Hernández, Venezuelan baseball player |
| 46573 | April 22 | Birth | 1980 – Kora Karvouni, Greek actress |
| 46574 | April 22 | Birth | 1980 – Aaron Michael Metchik, American actor and director |
| 46575 | April 22 | Birth | 1980 – Quincy Timberlake, Kenyan-Australian activist, engineer, and politician |
| 46576 | April 22 | Birth | 1981 – Ken Dorsey, American football player |
| 46577 | April 22 | Birth | 1981 – Daniel Ghiță, Romanian kick-boxer |
| 46578 | April 22 | Birth | 1981 – Madis Kallas, Estonian decathlete and activist |
| 46579 | April 22 | Birth | 1981 – Rafael Sperafico, Brazilian race car driver (d. 2007) |
| 46580 | April 22 | Birth | 1981 – Jonathan Trott, South African-English cricketer |
| 46581 | April 22 | Birth | 1982 – Kaká, Brazilian footballer |
| 46582 | April 22 | Birth | 1982 – Cassidy Freeman, American actress, singer, and pianist |
| 46583 | April 22 | Birth | 1982 – Joel Monaghan, Australian rugby player |
| 46584 | April 22 | Birth | 1982 – David Purcey, American baseball player |
| 46585 | April 22 | Birth | 1982 – Aidas Reklys, Lithuanian figure skater |
| 46586 | April 22 | Birth | 1982 – Aleksander Saharov, Estonian footballer |
| 46587 | April 22 | Birth | 1982 – Noriko Shitaya, Japanese voice actress |
| 46588 | April 22 | Birth | 1983 – Remi Ayodele, American football player |
| 46589 | April 22 | Birth | 1983 – Francis Capra, American actor |
| 46590 | April 22 | Birth | 1983 – Elliott Jordan, English actor |