| 95101 | August 21 | Death | 1622 – Juan de Tassis, 2nd Count of Villamediana, Spanish poet and politician (b. 1582) |
| 95102 | August 21 | Death | 1627 – Jacques Mauduit, French composer and academic (b. 1557) |
| 95103 | August 21 | Death | 1673 – Henry Grey, 1st Earl of Stamford, English soldier (b. 1599) |
| 95104 | August 21 | Death | 1689 – William Cleland, Scottish poet and soldier (b. 1661) |
| 95105 | August 21 | Death | 1762 – Lady Mary Wortley Montagu, English author, poet, and playwright (b. 1689) |
| 95106 | August 21 | Death | 1763 – Charles Wyndham, 2nd Earl of Egremont, English politician, Secretary of State for the Southern Department (b. 1710) |
| 95107 | August 21 | Death | 1775 – Zahir al-Umar, Arabian ruler (b. 1690) |
| 95108 | August 21 | Death | 1796 – John McKinly, American physician and politician, 1st Governor of Delaware (b. 1721) |
| 95109 | August 21 | Death | 1814 – Benjamin Thompson, American-English physicist and colonel (b. 1753) |
| 95110 | August 21 | Death | 1835 – John MacCulloch, Scottish geologist and academic (b. 1773) |
| 95111 | August 21 | Death | 1836 – Claude-Louis Navier, French physicist and engineer (b. 1785) |
| 95112 | August 21 | Death | 1838 – Adelbert von Chamisso, German botanist and poet (b. 1781) |
| 95113 | August 21 | Death | 1853 – Charles Tristan, marquis de Montholon, French general (b. 1783) |
| 95114 | August 21 | Death | 1854 – Thomas Clayton, American lawyer and politician (b. 1777) |
| 95115 | August 21 | Death | 1870 – Ma Xinyi, Chinese general and politician, Viceroy of Liangjiang (b. 1821) |
| 95116 | August 21 | Death | 1905 – Alexander von Oettingen, Estonian theologian and statistician (b. 1827) |
| 95117 | August 21 | Death | 1910 – Bertalan Székely, Hungarian painter and academic (b. 1835) |
| 95118 | August 21 | Death | 1919 – Laurence Doherty, English tennis player (b. 1875) |
| 95119 | August 21 | Death | 1935 – John Hartley, English tennis player (b. 1849) |
| 95120 | August 21 | Death | 1940 – Hermann Obrecht, Swiss lawyer and politician (b. 1882) |
| 95121 | August 21 | Death | 1940 – Ernest Thayer, American poet and author (b. 1863) |
| 95122 | August 21 | Death | 1940 – Leon Trotsky, Russian theorist and politician, founded the Red Army (b. 1879) |
| 95123 | August 21 | Death | 1943 – Henrik Pontoppidan, Danish journalist and author, Nobel Prize laureate (b. 1857) |
| 95124 | August 21 | Death | 1947 – Ettore Bugatti, Italian-French engineer and businessman, founded Bugatti (b. 1881) |
| 95125 | August 21 | Death | 1951 – Constant Lambert, English composer and conductor (b. 1905) |
| 95126 | August 21 | Death | 1957 – Mait Metsanurk, Estonian author and playwright (b. 1879) |
| 95127 | August 21 | Death | 1957 – Nels Stewart, Canadian ice hockey player (b. 1902) |
| 95128 | August 21 | Death | 1957 – Harald Sverdrup, Norwegian meteorologist and oceanographer (b. 1888) |
| 95129 | August 21 | Death | 1960 – David B. Steinman, American engineer, designed the Mackinac Bridge (b. 1886) |
| 95130 | August 21 | Death | 1964 – Palmiro Togliatti, Italian journalist and politician, Italian Minister of Justice (b. 1893) |