| 100441 | September 4 | Event | 1967 – Vietnam War: Operation Swift begins when U.S. Marines engage the North Vietnamese in battle in the Que Son Valley. |
| 100442 | September 4 | Event | 1970 – Salvador Allende is elected President of Chile. |
| 100443 | September 4 | Event | 1971 – Alaska Airlines Flight 1866 crashes near Juneau, Alaska, killing all 111 people on board. |
| 100444 | September 4 | Event | 1972 – Mark Spitz becomes the first competitor to win seven medals at a single Olympic Games. |
| 100445 | September 4 | Event | 1975 – The Sinai Interim Agreement relating to the Arab–Israeli conflict is signed. |
| 100446 | September 4 | Event | 1977 – The Golden Dragon massacre takes place in San Francisco. |
| 100447 | September 4 | Event | 1985 – The discovery of Buckminsterfullerene, the first fullerene molecule of carbon. |
| 100448 | September 4 | Event | 1989 – In Leipzig, East Germany, the first of weekly demonstration for the legalisation of opposition groups and democratic reforms takes place. |
| 100449 | September 4 | Event | 1996 – War on Drugs: Revolutionary Armed Forces of Colombia (FARC) attack a military base in Guaviare, starting three weeks of guerrilla warfare in which at least 130 Colombians are killed. |
| 100450 | September 4 | Event | 1998 – Google is founded by Larry Page and Sergey Brin, two students at Stanford University. |
| 100451 | September 4 | Event | 2001 – Tokyo DisneySea opens to the public as part of the Tokyo Disney Resort in Urayasu, Chiba, Japan. |
| 100452 | September 4 | Event | 2007 – Three terrorists suspected to be a part of Al-Qaeda are arrested in Germany after allegedly planning attacks on both the Frankfurt International airport and US military installations. |
| 100453 | September 4 | Event | 2010 – A 7.1 magnitude earthquake strikes the South Island of New Zealand causing widespread damage and several power outages. |
| 100454 | September 4 | Birth | 1241 – Alexander III of Scotland (d. 1286) |
| 100455 | September 4 | Birth | 1383 – Antipope Felix V (d. 1451) |
| 100456 | September 4 | Birth | 1454 – Henry Stafford, 2nd Duke of Buckingham, English politician, Lord High Constable of England (d. 1483) |
| 100457 | September 4 | Birth | 1557 – Sophie of Mecklenburg-Güstrow (d. 1631) |
| 100458 | September 4 | Birth | 1563 – Wanli Emperor of China (d. 1620) |
| 100459 | September 4 | Birth | 1596 – Constantijn Huygens, Dutch poet and composer (d. 1687) |
| 100460 | September 4 | Birth | 1681 – Carl Heinrich Biber, Austrian violinist and composer (d. 1749) |
| 100461 | September 4 | Birth | 1717 – Job Orton, English minister and author (d. 1783) |
| 100462 | September 4 | Birth | 1755 – Axel von Fersen the Younger, Swedish general and politician (d. 1810) |
| 100463 | September 4 | Birth | 1768 – François-René de Chateaubriand, French historian and politician, Minister of Foreign Affairs for France (d. 1848) |
| 100464 | September 4 | Birth | 1776 – Stephen Whitney, American businessman (d. 1860) |
| 100465 | September 4 | Birth | 1798 – Raynold Kaufgetz, Swiss soldier, economist, and politician (d. 1869) |
| 100466 | September 4 | Birth | 1803 – Sarah Childress Polk, American wife of James K. Polk, 14th First Lady of the United States (d. 1891) |
| 100467 | September 4 | Birth | 1809 – Manuel Montt, Chilean scholar and politician, 6th President of Chile (d. 1880) |
| 100468 | September 4 | Birth | 1809 – Juliusz Słowacki, Polish poet and playwright (d. 1849) |
| 100469 | September 4 | Birth | 1824 – Anton Bruckner, Austrian organist and composer (d. 1896) |
| 100470 | September 4 | Birth | 1825 – Dadabhai Naoroji, Indian academic and politician, President of the Indian National Congress (d. 1917) |