| 31921 | March 22 | Birth | 1503 – Antonio Francesco Grazzini, Italian author and educator (d. 1583) |
| 31922 | March 22 | Birth | 1599 – Anthony van Dyck, Flemish-English painter and etcher (d. 1641) |
| 31923 | March 22 | Birth | 1609 – John II Casimir Vasa, Polish king (d. 1672) |
| 31924 | March 22 | Birth | 1663 – August Hermann Francke, German clergyman, philanthropist, and scholar (d. 1727) |
| 31925 | March 22 | Birth | 1684 – William Pulteney, 1st Earl of Bath, English politician, Secretary at War (d. 1764) |
| 31926 | March 22 | Birth | 1712 – Edward Moore, English poet and playwright (d. 1757) |
| 31927 | March 22 | Birth | 1720 – Nicolas-Henri Jardin, French architect, designed the Yellow Palace and Bernstorff Palace (d. 1799) |
| 31928 | March 22 | Birth | 1723 – Charles Carroll, American lawyer and politician (d. 1783) |
| 31929 | March 22 | Birth | 1728 – Anton Raphael Mengs, German painter and theorist (d. 1779) |
| 31930 | March 22 | Birth | 1759 – Hedvig Elisabeth Charlotte of Holstein-Gottorp (d. 1818) |
| 31931 | March 22 | Birth | 1797 – William I, German Emperor (d. 1888) |
| 31932 | March 22 | Birth | 1808 – David Swinson Maynard, American physician and lawyer (d. 1873) |
| 31933 | March 22 | Birth | 1812 – Stephen Pearl Andrews, American author and activist (d. 1886) |
| 31934 | March 22 | Birth | 1814 – Thomas Crawford, American sculptor, designed the Statue of Freedom (d. 1857) |
| 31935 | March 22 | Birth | 1817 – Braxton Bragg, American general (d. 1876) |
| 31936 | March 22 | Birth | 1818 – John Ainsworth Horrocks, English-Australian explorer, founded Penwortham (d. 1846) |
| 31937 | March 22 | Birth | 1837 – Virginia Oldoini, Countess of Castiglione (d. 1899) |
| 31938 | March 22 | Birth | 1842 – Mykola Lysenko, Ukrainian pianist, composer, and conductor (d. 1912) |
| 31939 | March 22 | Birth | 1846 – Randolph Caldecott, English illustrator and painter (d. 1886) |
| 31940 | March 22 | Birth | 1846 – James Timberlake, American lieutenant, police officer, and farmer (d. 1891) |
| 31941 | March 22 | Birth | 1852 – Otakar Ševčík, Czech violinist and educator (d. 1934) |
| 31942 | March 22 | Birth | 1852 – Hector Sévin, French cardinal (d. 1916) |
| 31943 | March 22 | Birth | 1857 – Paul Doumer, French mathematician, journalist, and politician, 14th President of France (d. 1932) |
| 31944 | March 22 | Birth | 1866 – Jack Boyle, American baseball player and umpire (d. 1913) |
| 31945 | March 22 | Birth | 1868 – Robert Andrews Millikan, American colonel and physicist, Nobel Prize laureate (d. 1953) |
| 31946 | March 22 | Birth | 1869 – Tom McInnes, Scottish-English footballer (d. 1939) |
| 31947 | March 22 | Birth | 1873 – Ernest Lawson, Canadian-American painter (d. 1939) |
| 31948 | March 22 | Birth | 1878 – Michel Théato, Luxembourgian-French runner (d. 1919) |
| 31949 | March 22 | Birth | 1880 – Ernest C. Quigley, Canadian-American football player and coach (d. 1960) |
| 31950 | March 22 | Birth | 1884 – Arthur H. Vandenberg, American journalist and politician (d. 1951) |