| 39901 | April 7 | Event | 1724 – Premiere performance of Johann Sebastian Bach's St John Passion BWV 245 at St. Nicholas Church, Leipzig. |
| 39902 | April 7 | Event | 1767 – End of Burmese–Siamese War (1765–67). |
| 39903 | April 7 | Event | 1776 – Captain John Barry and the USS Lexington captures the Edward. |
| 39904 | April 7 | Event | 1788 – American pioneers to the Northwest Territory arrive at the confluence of the Ohio and Muskingum rivers, establishing Marietta, Ohio, as the first permanent American settlement of the new United States in the Northwest Territory, and opening the wes |
| 39905 | April 7 | Event | 1789 – Selim III became Sultan of the Ottoman Empire and Caliph of Islam. |
| 39906 | April 7 | Event | 1798 – The Mississippi Territory is organized from disputed territory claimed by both the United States and Spain. It is expanded in 1804 and again in 1812. |
| 39907 | April 7 | Event | 1805 – Lewis and Clark Expedition: The Corps of Discovery breaks camp among the Mandan tribe and resumes its journey West along the Missouri River. |
| 39908 | April 7 | Event | 1805 – German composer Ludwig van Beethoven premiered his Third Symphony, at the Theater an der Wien in Vienna. |
| 39909 | April 7 | Event | 1827 – John Walker, an English chemist, sells the first friction match that he had invented the previous year. |
| 39910 | April 7 | Event | 1829 – Joseph Smith, founder of the Latter Day Saint movement, commences translation of the Book of Mormon, with Oliver Cowdery as his scribe. |
| 39911 | April 7 | Event | 1831 – Emperor Pedro I of Brazil resigns. He goes to his native Portugal to become King Pedro IV. |
| 39912 | April 7 | Event | 1862 – American Civil War: Battle of Shiloh ends: The Union Army under General Ulysses S. Grant defeats the Confederates near Shiloh, Tennessee. |
| 39913 | April 7 | Event | 1868 – Thomas D'Arcy McGee, one of the Canadian Fathers of Confederation is assassinated by Irish Republicans, in one of the few Canadian political assassinations, and the only one of a federal politician. |
| 39914 | April 7 | Event | 1890 – Completion of the first Lake Biwa Canal. |
| 39915 | April 7 | Event | 1906 – Mount Vesuvius erupts and devastates Naples. |
| 39916 | April 7 | Event | 1906 – The Algeciras Conference gives France and Spain control over Morocco. |
| 39917 | April 7 | Event | 1908 – H. H. Asquith of the Liberal Party takes office as Prime Minister of the United Kingdom, succeeding Sir Henry Campbell-Bannerman. |
| 39918 | April 7 | Event | 1922 – Teapot Dome scandal: United States Secretary of the Interior leases Teapot Dome petroleum reserves in Wyoming. |
| 39919 | April 7 | Event | 1927 – First long-distance public television broadcast (from Washington, D.C., to New York City, displaying the image of Commerce Secretary Herbert Hoover). |
| 39920 | April 7 | Event | 1933 – Prohibition in the United States is repealed for beer of no more than 3.2% alcohol by weight, eight months before the ratification of the XXI amendment. |
| 39921 | April 7 | Event | 1939 – World War II: Italy invades Albania. |
| 39922 | April 7 | Event | 1940 – Booker T. Washington becomes the first African American to be depicted on a United States postage stamp. |
| 39923 | April 7 | Event | 1943 – The Holocaust: In Terebovlia, Ukraine, Germans order 1,100 Jews to undress to their underwear and march through the city of Terebovlia to the nearby village of Plebanivka where they are shot dead and buried in ditches. |
| 39924 | April 7 | Event | 1943 – Ioannis Rallis becomes collaborationist Prime Minister of Greece during the Axis Occupation. |
| 39925 | April 7 | Event | 1945 – World War II: The Japanese battleship Yamato, the largest battleship ever constructed, is sunk by American planes 200 miles north of Okinawa while en route to a suicide mission in Operation Ten-Go. |
| 39926 | April 7 | Event | 1945 – World War II: Visoko is liberated by the 7th, 9th, and 17th Krajina brigades from the Tenth division of Yugoslav Partisan forces. |
| 39927 | April 7 | Event | 1946 – Syria's independence from France is officially recognised. |
| 39928 | April 7 | Event | 1948 – The World Health Organization is established by the United Nations. |
| 39929 | April 7 | Event | 1948 – A Buddhist monastery burns in Shanghai, China, leaving twenty monks dead. |
| 39930 | April 7 | Event | 1954 – United States President Dwight D. Eisenhower gives his "domino theory" speech during a news conference. |