| 4141 | January 10 | Event | 1962 – Apollo program: NASA announces plans to build the C-5 rocket launch vehicle. It became better known as the Saturn V Moon rocket, which launched every Apollo Moon mission. |
| 4142 | January 10 | Event | 1971 – A by-poll is held in the Lebanese Chouf District. |
| 4143 | January 10 | Event | 1972 – Sheikh Mujibur Rahman returns to the newly independent Bangladesh as president after spending over nine months in prison in Pakistan. |
| 4144 | January 10 | Event | 1981 – Salvadoran Civil War: The FMLN launches its first major offensive, gaining control of most of Morazán and Chalatenango departments |
| 4145 | January 10 | Event | 1984 – Holy See–United States relations: The United States and Holy See (Vatican City) re-establish full diplomatic relations after almost 117 years, overturning the United States Congress's 1867 ban on public funding for such a diplomatic envoy. |
| 4146 | January 10 | Event | 1985 – Sir Clive Sinclair launches the Sinclair C5 personal electric vehicle, which became a notorious commercial failure and later a cult collector's item. |
| 4147 | January 10 | Event | 1985 – Sandinista Daniel Ortega becomes president of Nicaragua and vows to continue the transformation to socialism and alliance with the Soviet Union and Cuba American policy continues to support the Contras in their revolt against the Nicaraguan governm |
| 4148 | January 10 | Event | 1990 – Time Warner is formed by the merger of Time Inc. and Warner Communications. |
| 4149 | January 10 | Event | 1999 – Sanjeev Nanda kills three policemen in New Delhi, India with his car, an act for which he was later acquitted, resulting in a sharp drop in public confidence in the Indian legal system. |
| 4150 | January 10 | Event | 2005 – A mudslide occurs in La Conchita, California, killing 10 people, injuring many more and closing U.S. Route 101, the main coastal corridor between Los Angeles and San Francisco for 10 days. |
| 4151 | January 10 | Event | 2007 – A general strike begins in Guinea in an eventually successful attempt to get President Lansana Conté to resign. |
| 4152 | January 10 | Event | 2011 – 2010–11 Queensland floods: Torrential rain in the Lockyer Valley region of South East Queensland, Australia, causes severe flash flooding, killing 9 people. |
| 4153 | January 10 | Event | 2012 – A bombing in Khyber Agency, Pakistan, kills at least 30 people and 78 others injured. |
| 4154 | January 10 | Event | 2013 – More than 100 people are killed and 270 injured in several bomb blasts in Pakistan. |
| 4155 | January 10 | Event | 2015 – A mass poisoning at a funeral in Mozambique involves beer that was deliberately contaminated with crocodile bile leaving at least 56 dead and nearly 200 hospitalized. |
| 4156 | January 10 | Event | 2015 – A traffic accident between an oil tanker truck and passenger coach en route to Shikarpur from Karachi on the Pakistan National Highway Link Road near Gulshan-e-Hadeed, Karachi, kills at least 62 people. |
| 4157 | January 10 | Birth | 1480 – Margaret of Austria, Duchess of Savoy (d. 1530) |
| 4158 | January 10 | Birth | 1538 – Louis of Nassau (d. 1574) |
| 4159 | January 10 | Birth | 1607 – Isaac Jogues, French priest and missionary (d. 1646) |
| 4160 | January 10 | Birth | 1628 – George Villiers, 2nd Duke of Buckingham, English politician, Lord Lieutenant of the West Riding of Yorkshire (d. 1687) |
| 4161 | January 10 | Birth | 1644 – Louis François, duc de Boufflers, French general (d. 1711) |
| 4162 | January 10 | Birth | 1654 – Joshua Barnes, English historian and scholar (d. 1712) |
| 4163 | January 10 | Birth | 1702 – Johannes Zick, German painter (d. 1762) |
| 4164 | January 10 | Birth | 1715 – Christian August Crusius, German philosopher and theologian (d. 1775) |
| 4165 | January 10 | Birth | 1729 – Lazzaro Spallanzani, Italian priest, biologist, and physiologist (d. 1799) |
| 4166 | January 10 | Birth | 1741 – Princess Elizabeth of Great Britain (d. 1759) |
| 4167 | January 10 | Birth | 1745 – Isaac Titsingh, Dutch surgeon, scholar, and diplomat (d. 1812) |
| 4168 | January 10 | Birth | 1750 – Thomas Erskine, 1st Baron Erskine, Scottish-English lawyer and politician, Lord Chancellor of Great Britain (d. 1823) |
| 4169 | January 10 | Birth | 1760 – Johann Rudolf Zumsteeg, German composer and conductor (d. 1802) |
| 4170 | January 10 | Birth | 1769 – Michel Ney, French general (d. 1815) |