| 42271 | April 12 | Birth | 1991 – Oliver Norwood, English footballer |
| 42272 | April 12 | Birth | 1991 – Magnus Pääjärvi, Swedish ice hockey player |
| 42273 | April 12 | Birth | 1991 – Jazz Richards, Welsh footballer |
| 42274 | April 12 | Birth | 1992 – Giorgio Cantarini, Italian actor |
| 42275 | April 12 | Birth | 1992 – Chad le Clos, South African swimmer |
| 42276 | April 12 | Birth | 1993 – Jordan Archer, English-Scottish footballer |
| 42277 | April 12 | Birth | 1993 – Dorial Green-Beckham, American football player |
| 42278 | April 12 | Birth | 1993 – Ryan Nugent-Hopkins, Canadian ice hockey player |
| 42279 | April 12 | Birth | 1993 – Katelyn Pippy, American ice hockey player and actress |
| 42280 | April 12 | Birth | 1994 – Isabelle Drummond, Brazilian actress and singer |
| 42281 | April 12 | Birth | 1994 – Saoirse Ronan, American-Irish actress |
| 42282 | April 12 | Birth | 1994 – Airi Suzuki, Japanese actress and singer (Aa!, Cute, and Buono!) |
| 42283 | April 12 | Birth | 1996 – Elizaveta Kulichkova, Russian tennis player |
| 42284 | April 12 | Birth | 1997 – Katelyn Ohashi, American gymnast |
| 42285 | April 12 | Birth | 1999 – Akai Osei, English actor, singer, and dancer |
| 42286 | April 12 | Birth | 2000 – Suzanna von Nathusius, Polish actress |
| 42287 | April 12 | Death | 45 BC – Gnaeus Pompeius, Roman general and politician (b. 75 BC) |
| 42288 | April 12 | Death | 238 – Gordian I, Roman emperor (b. 159) |
| 42289 | April 12 | Death | 238 – Gordian II, Roman emperor (b. 192) |
| 42290 | April 12 | Death | 352 – Pope Julius I |
| 42291 | April 12 | Death | 434 – Archbishop Maximianus of Constantinople |
| 42292 | April 12 | Death | 1125 – Vladislaus I, Duke of Bohemia (b. 1065) |
| 42293 | April 12 | Death | 1443 – Henry Chichele, English archbishop (b. 1364) |
| 42294 | April 12 | Death | 1550 – Claude, Duke of Guise (b. 1496) |
| 42295 | April 12 | Death | 1555 – Joanna of Castile (b. 1479) |
| 42296 | April 12 | Death | 1675 – Richard Bennett, English politician, colonial Governor of Virginia (b. 1609) |
| 42297 | April 12 | Death | 1684 – Nicola Amati, Italian instrument maker (b. 1596) |
| 42298 | April 12 | Death | 1687 – Ambrose Dixon, English-American soldier (b. 1619) |
| 42299 | April 12 | Death | 1704 – Jacques-Bénigne Bossuet, French bishop and theologian (b. 1627) |
| 42300 | April 12 | Death | 1748 – William Kent, English architect, designed Holkham Hall and Chiswick House (b. 1685) |