| 48391 | April 27 | Birth | 1737 – Edward Gibbon, English historian and politician (d. 1794) |
| 48392 | April 27 | Birth | 1748 – Adamantios Korais, Greek-French philosopher and scholar (d. 1833) |
| 48393 | April 27 | Birth | 1755 – Marc-Antoine Parseval, French mathematician and theorist (d. 1836) |
| 48394 | April 27 | Birth | 1759 – Mary Wollstonecraft, English philosopher, historian, and author (d. 1797) |
| 48395 | April 27 | Birth | 1788 – Charles Robert Cockerell, English architect, archaeologist, and writer (d. 1863) |
| 48396 | April 27 | Birth | 1791 – Samuel Morse, American painter and inventor, co-invented the Morse code (d. 1872) |
| 48397 | April 27 | Birth | 1806 – Maria Christina of the Two Sicilies (d. 1878) |
| 48398 | April 27 | Birth | 1812 – William W. Snow, American lawyer and politician (d. 1886) |
| 48399 | April 27 | Birth | 1812 – Friedrich von Flotow, German composer (d. 1883) |
| 48400 | April 27 | Birth | 1820 – Herbert Spencer, English biologist, anthropologist, sociologist, and philosopher (d. 1903) |
| 48401 | April 27 | Birth | 1822 – Ulysses S. Grant, American general and politician, 18th President of the United States (d. 1885) |
| 48402 | April 27 | Birth | 1840 – Edward Whymper, English-French mountaineer, explorer, author, and illustrator (d. 1911) |
| 48403 | April 27 | Birth | 1848 – Otto of Bavaria (d. 1916) |
| 48404 | April 27 | Birth | 1850 – Hans Hartwig von Beseler, German general and politician (d. 1921) |
| 48405 | April 27 | Birth | 1853 – Jules Lemaître, French playwright and critic (d. 1914) |
| 48406 | April 27 | Birth | 1857 – Theodor Kittelsen, Norwegian painter and illustrator (d. 1914) |
| 48407 | April 27 | Birth | 1861 – William Arms Fisher, American composer and music historian (d. 1948) |
| 48408 | April 27 | Birth | 1862 – Rudolph Schildkraut, Turkish-American actor (d. 1930) |
| 48409 | April 27 | Birth | 1866 – Maurice Raoul-Duval, French polo player (d. 1916) |
| 48410 | April 27 | Birth | 1875 – Frederick Fane, Irish-born, English cricketer (d. 1960) |
| 48411 | April 27 | Birth | 1876 – Con Leahy, Irish athlete (d. 1921) |
| 48412 | April 27 | Birth | 1878 – John Rimmer, English runner (d. 1962) |
| 48413 | April 27 | Birth | 1880 – Mihkel Lüdig, Estonian organist, composer, and conductor (d. 1958) |
| 48414 | April 27 | Birth | 1882 – Jessie Redmon Fauset, American author and poet (d. 1961) |
| 48415 | April 27 | Birth | 1887 – Warren Wood, American golfer (d. 1926) |
| 48416 | April 27 | Birth | 1888 – Florence La Badie, Canadian actress (d. 1917) |
| 48417 | April 27 | Birth | 1893 – Draža Mihailović, Serbian general (d. 1946) |
| 48418 | April 27 | Birth | 1893 – Allen Sothoron, American baseball player, coach, and manager (d. 1939) |
| 48419 | April 27 | Birth | 1894 – George Petty, American painter and illustrator (d. 1975) |
| 48420 | April 27 | Birth | 1894 – Nicolas Slonimsky, Russian pianist, composer, and conductor (d. 1995) |