| 48751 | April 28 | Event | 1986 – The United States Navy aircraft carrier USS Enterprise becomes the first nuclear-powered aircraft carrier to transit the Suez Canal, navigating from the Red Sea to the Mediterranean Sea to relieve the USS Coral Sea. |
| 48752 | April 28 | Event | 1986 – High levels of radiation resulting from the Chernobyl disaster are detected at a nuclear power plant in Sweden, leading Soviet authorities to publicly announce the accident. |
| 48753 | April 28 | Event | 1987 – American engineer Ben Linder is killed in an ambush by U.S.-funded Contras in northern Nicaragua. |
| 48754 | April 28 | Event | 1988 – Near Maui, Hawaii, flight attendant Clarabelle "C.B." Lansing is blown out of Aloha Airlines Flight 243, a Boeing 737, and falls to her death when part of the plane's fuselage rips open in mid-flight. |
| 48755 | April 28 | Event | 1994 – Former Central Intelligence Agency counterintelligence officer and analyst Aldrich Ames pleads guilty to giving U.S. secrets to the Soviet Union and later Russia. |
| 48756 | April 28 | Event | 1996 – Whitewater controversy: President Bill Clinton gives a 4½ hour videotaped testimony for the defense. |
| 48757 | April 28 | Event | 1996 – Port Arthur massacre, Tasmania: A gunman, Martin Bryant, opens fire at the Broad Arrow Cafe in Port Arthur, Tasmania, killing 35 people and wounding 23 others. |
| 48758 | April 28 | Event | 2001 – Dennis Tito becomes the world's first space tourist. |
| 48759 | April 28 | Birth | 32 – Otho, Roman emperor (d. 69 AD) |
| 48760 | April 28 | Birth | 1442 – Edward IV of England (d. 1483) |
| 48761 | April 28 | Birth | 1545 – Yi Sun-sin, Korean commander (d. 1598) |
| 48762 | April 28 | Birth | 1630 – Charles Cotton, English poet and author (d. 1687) |
| 48763 | April 28 | Birth | 1652 – Magdalena Sibylla of Hesse-Darmstadt (d. 1712) |
| 48764 | April 28 | Birth | 1686 – Michael Brokoff, Czech sculptor (d. 1721) |
| 48765 | April 28 | Birth | 1715 – Franz Sparry, Austrian composer and educator (d. 1767) |
| 48766 | April 28 | Birth | 1758 – James Monroe, American soldier, lawyer, and politician, 5th President of the United States (d. 1831) |
| 48767 | April 28 | Birth | 1765 – Sylvestre François Lacroix, French mathematician and academic (d. 1834) |
| 48768 | April 28 | Birth | 1819 – Ezra Abbot, American scholar and academic (d. 1884) |
| 48769 | April 28 | Birth | 1827 – William Hall, Canadian soldier, Victoria Cross recipient (d. 1904) |
| 48770 | April 28 | Birth | 1838 – Tobias Asser, Dutch lawyer and scholar, Nobel Prize laureate (d. 1913) |
| 48771 | April 28 | Birth | 1848 – Ludvig Schytte, Danish pianist, composer, and educator (d. 1909) |
| 48772 | April 28 | Birth | 1855 – José Malhoa, Portuguese painter (d. 1933) |
| 48773 | April 28 | Birth | 1863 – Josiah Thomas, English-Australian miner and politician, 7th Australian Minister for Foreign Affairs (d. 1933) |
| 48774 | April 28 | Birth | 1865 – Charles W. Woodworth, American entomologist and academic (d. 1940) |
| 48775 | April 28 | Birth | 1868 – Lucy Booth, English composer (d. 1953) |
| 48776 | April 28 | Birth | 1868 – Hélène de Pourtalès, Swiss sailor (d. 1945) |
| 48777 | April 28 | Birth | 1868 – Georgy Voronoy, Ukrainian-Russian mathematician and academic (d. 1908) |
| 48778 | April 28 | Birth | 1874 – Karl Kraus, Austrian journalist and author (d. 1936) |
| 48779 | April 28 | Birth | 1874 – Sidney Toler, American actor and director (d. 1947) |
| 48780 | April 28 | Birth | 1876 – Nicola Romeo, Italian engineer and businessman (d. 1938) |