| 58231 | May.21 | Birth | 1981 – Edson Buddle, American soccer player |
| 58232 | May.21 | Birth | 1981 – Josh Hamilton, American baseball player |
| 58233 | May.21 | Birth | 1981 – Maximilian Mutzke, German singer-songwriter |
| 58234 | May.21 | Birth | 1981 – Anna Rogowska, Polish pole vaulter |
| 58235 | May.21 | Birth | 1981 – Kaori Shimizu, Japanese voice actress and singer |
| 58236 | May.21 | Birth | 1982 – Brian Klemm, American singer-songwriter and guitarist (Suburban Legends and Big D and the Kids Table) |
| 58237 | May.21 | Birth | 1983 – Līga Dekmeijere, Latvian tennis player |
| 58238 | May.21 | Birth | 1983 – Deidson Araújo Maia, Brazilian footballer |
| 58239 | May.21 | Birth | 1984 – Lorena Ayala, Dutch model |
| 58240 | May.21 | Birth | 1984 – Brandon Fields, American football player |
| 58241 | May.21 | Birth | 1984 – Sara Goller, German volleyball player |
| 58242 | May.21 | Birth | 1985 – Kano, English rapper, producer, and actor |
| 58243 | May.21 | Birth | 1985 – Mutya Buena, English singer-songwriter (Sugababes and Mutya Keisha Siobhan) |
| 58244 | May.21 | Birth | 1985 – Marco Carta, Italian singer |
| 58245 | May.21 | Birth | 1985 – Mark Cavendish, Manx cyclist |
| 58246 | May.21 | Birth | 1985 – Alexander Dale Oen, Norwegian swimmer (d. 2012) |
| 58247 | May.21 | Birth | 1985 – Isa Guha, English cricketer |
| 58248 | May.21 | Birth | 1985 – Lucie Hradecká, Czech tennis player |
| 58249 | May.21 | Birth | 1985 – Dušan Kuciak, Solvak footballer |
| 58250 | May.21 | Birth | 1985 – Marie McCray, American porn actress and model |
| 58251 | May.21 | Birth | 1985 – Andrew Miller, American baseball player |
| 58252 | May.21 | Birth | 1986 – Myra, American singer and actress |
| 58253 | May.21 | Birth | 1986 – Konstantinos Argyros, Greek singer |
| 58254 | May.21 | Birth | 1986 – Mario Mandžukić, Croatian footballer |
| 58255 | May.21 | Birth | 1986 – Alexander Noyes, American drummer (Honor Society) |
| 58256 | May.21 | Birth | 1986 – Eder Sánchez, Mexican race walker |
| 58257 | May.21 | Birth | 1986 – Park Sojin, South Korean singer-songwriter and dancer (Girl's Day) |
| 58258 | May.21 | Birth | 1986 – Greg Stewart, Canadian ice hockey player |
| 58259 | May.21 | Birth | 1988 – Claire Cashmore, English swimmer |
| 58260 | May.21 | Birth | 1988 – Park Gyu-ri, South Korean singer and actress (Kara) |