| 9241 | January 22 | Event | 1946 – In Iran, Qazi Muhammad declares the independent people's Republic of Mahabad at Chahar Cheragh Square in the Kurdish city of Mahabad. He is the new president and Haji Baba Sheikh is the prime minister. |
| 9242 | January 22 | Event | 1946 – Creation of the Central Intelligence Group, forerunner of the Central Intelligence Agency. |
| 9243 | January 22 | Event | 1947 – KTLA, the first commercial television station west of the Mississippi River, begins operation in Hollywood. |
| 9244 | January 22 | Event | 1957 – Israel withdraws from the Sinai Peninsula. |
| 9245 | January 22 | Event | 1957 – The New York City "Mad Bomber", George P. Metesky, is arrested in Waterbury, Connecticut and is charged with planting more than 30 bombs. |
| 9246 | January 22 | Event | 1959 – Knox Mine disaster: Water breaches the River Slope Mine near Pittston, Pennsylvania in Port Griffith 12 miners are killed. |
| 9247 | January 22 | Event | 1962 – The Organization of American States suspends Cuba's membership. |
| 9248 | January 22 | Event | 1963 – The Élysée Treaty of cooperation between France and Germany is signed by Charles de Gaulle and Konrad Adenauer. |
| 9249 | January 22 | Event | 1968 – Apollo 5 lifts off carrying the first Lunar module into space. |
| 9250 | January 22 | Event | 1968 – Operation Igloo White, a US electronic surveillance system to stop communist infiltration into South Vietnam begins installation. |
| 9251 | January 22 | Event | 1969 – A gunman attempts to assassinate Soviet leader Leonid Brezhnev. |
| 9252 | January 22 | Event | 1970 – The Boeing 747, the world's first "jumbo jet", enters commercial service for launch customer Pan American Airways with its maiden voyage from John F. Kennedy International Airport to London Heathrow Airport. |
| 9253 | January 22 | Event | 1971 – The Singapore Declaration, one of the two most important documents to the uncodified constitution of the Commonwealth of Nations, is issued. |
| 9254 | January 22 | Event | 1973 – The Supreme Court of the United States delivers its decisions in Roe v. Wade and Doe v. Bolton, legalizing elective abortion in all fifty states. |
| 9255 | January 22 | Event | 1973 – The crew of Apollo 17 addresses a joint session of Congress after the completion of the final Apollo moon landing mission. |
| 9256 | January 22 | Event | 1973 – A chartered Boeing 707 explodes in flames upon landing at Kano Airport, Nigeria, killing 176. |
| 9257 | January 22 | Event | 1984 – The Apple Macintosh, the first consumer computer to popularize the computer mouse and the graphical user interface, is introduced during Super Bowl XVIII with its famous "1984" television commercial. |
| 9258 | January 22 | Event | 1987 – Pennsylvania politician R. Budd Dwyer shoots and kills himself during a televised press conference, leading to debates on boundaries in journalism. |
| 9259 | January 22 | Event | 1987 – Philippine security forces open fire on a crowd of 10,000–15,000 demonstrators at Malacañang Palace, Manila, killing 13. |
| 9260 | January 22 | Event | 1990 – Robert Tappan Morris is convicted of releasing the 1988 Internet Computer worm. |
| 9261 | January 22 | Event | 1991 – Gulf War: Three Scuds and one Patriot missile hit Ramat Gan in Israel, injuring 96 people. Three elderly people die of heart attacks. |
| 9262 | January 22 | Event | 1992 – Rebel forces occupy Zaire's national radio station in Kinshasa and broadcast a demand for the government's resignation. |
| 9263 | January 22 | Event | 1992 – Space Shuttle program: Dr. Roberta Bondar becomes the first Canadian woman and the first neurologist in space. |
| 9264 | January 22 | Event | 1995 – Israeli–Palestinian conflict: Beit Lid massacre: In central Israel, near Netanya, two suicide bombers from the Gaza Strip blow themselves up at a military transit point killing 19 Israelis. |
| 9265 | January 22 | Event | 1999 – Australian missionary Graham Staines and his two sons are burned alive by radical Hindus while sleeping in their car in Eastern India. |
| 9266 | January 22 | Event | 2002 – Kmart becomes the largest retailer in United States history to file for Chapter 11 bankruptcy protection. |
| 9267 | January 22 | Event | 2006 – Evo Morales is inaugurated as President of Bolivia, becoming the country's first indigenous president. |
| 9268 | January 22 | Event | 2006 – Kobe Bryant of the Los Angeles Lakers scores 81 points in an NBA game versus the Toronto Raptors, the second highest total in NBA history. |
| 9269 | January 22 | Event | 2007 – At least 88 people are killed when two car bombs explode in the Bab Al-Sharqi market in central Baghdad, Iraq. |
| 9270 | January 22 | Event | 2010 – Conan O'Brien performs his last Tonight Show on NBC as a part of the 2010 Tonight Show conflict. |