| 94861 | August 21 | Birth | 1597 – Roger Twysden, English historian and politician (d. 1672) |
| 94862 | August 21 | Birth | 1643 – Afonso VI of Portugal (d. 1683) |
| 94863 | August 21 | Birth | 1660 – Hubert Gautier, French mathematician and engineer (d. 1737) |
| 94864 | August 21 | Birth | 1665 – Giacomo F. Maraldi, French-Italian astronomer and mathematician (d. 1729) |
| 94865 | August 21 | Birth | 1670 – James FitzJames, 1st Duke of Berwick, French general and politician, Lord Lieutenant of Hampshire (d. 1734) |
| 94866 | August 21 | Birth | 1725 – Jean-Baptiste Greuze, French painter and educator (d. 1805) |
| 94867 | August 21 | Birth | 1754 – William Murdoch, Scottish engineer and inventor, created gas lighting (d. 1839) |
| 94868 | August 21 | Birth | 1754 – Banastre Tarleton, English general and politician (d. 1833) |
| 94869 | August 21 | Birth | 1765 – William IV of the United Kingdom (d. 1837) |
| 94870 | August 21 | Birth | 1789 – Augustin-Louis Cauchy, French mathematician and academic (d. 1857) |
| 94871 | August 21 | Birth | 1798 – Jules Michelet, French historian and philosopher (d. 1874) |
| 94872 | August 21 | Birth | 1800 – Hiram Walden, American general and politician (d. 1880) |
| 94873 | August 21 | Birth | 1801 – Guillaume Groen van Prinsterer, Dutch historian and politician (d. 1876) |
| 94874 | August 21 | Birth | 1813 – Jean Stas, Belgian chemist and physician (d. 1891) |
| 94875 | August 21 | Birth | 1816 – Charles Frédéric Gerhardt, French chemist and academic (d. 1856) |
| 94876 | August 21 | Birth | 1823 – Nathaniel Everett Green, English painter and astronomer (d. 1899) |
| 94877 | August 21 | Birth | 1826 – Karl Gegenbaur, German anatomist and academic (d. 1903) |
| 94878 | August 21 | Birth | 1840 – Ferdinand Hamer, Dutch bishop and missionary (d. 1900) |
| 94879 | August 21 | Birth | 1858 – Rudolf, Crown Prince of Austria (d. 1889) |
| 94880 | August 21 | Birth | 1862 – Emilio Salgari, Italian journalist and author (d. 1911) |
| 94881 | August 21 | Birth | 1869 – William Henry Ogilvie, Scottish-Australian poet and author (d. 1963) |
| 94882 | August 21 | Birth | 1872 – Aubrey Beardsley, English author and illustrator (d. 1898) |
| 94883 | August 21 | Birth | 1878 – Richard Girulatis, German footballer and manager (d. 1963) |
| 94884 | August 21 | Birth | 1879 – Claude Grahame-White, English pilot and engineer (d. 1959) |
| 94885 | August 21 | Birth | 1884 – Chandler Egan, American golfer and architect (d. 1936) |
| 94886 | August 21 | Birth | 1885 – Édouard Fabre, Canadian runner (d. 1939) |
| 94887 | August 21 | Birth | 1886 – Ruth Manning-Sanders, Welsh-English author and poet (d. 1988) |
| 94888 | August 21 | Birth | 1887 – James Paul Moody, English sailor (d. 1912) |
| 94889 | August 21 | Birth | 1891 – Emiliano Mercado del Toro, Puerto Rican soldier (d. 2007) |
| 94890 | August 21 | Birth | 1892 – Charles Vanel, French actor and director (d. 1989) |