| 95221 | August 22 | Event | 1922 – Michael Collins, Commander-in-chief of the Irish Free State Army, is shot dead during an Anti-Treaty ambush at Béal na Bláth, County Cork, during the Irish Civil War. |
| 95222 | August 22 | Event | 1932 – The BBC first experiments with television broadcasting. (See also Timeline of the BBC.) |
| 95223 | August 22 | Event | 1934 – Bill Woodfull of Australia becomes the only cricket captain to twice regain The Ashes. |
| 95224 | August 22 | Event | 1941 – World War II: German troops reach Leningrad, leading to the siege of Leningrad. |
| 95225 | August 22 | Event | 1942 – World War II: Brazil declares war on Germany and Italy. |
| 95226 | August 22 | Event | 1944 – World War II: Romania is captured by the Soviet Union. |
| 95227 | August 22 | Event | 1944 – World War II: Holocaust of Kedros in Crete by German forces |
| 95228 | August 22 | Event | 1949 – Queen Charlotte earthquake: Canada's largest earthquake since the 1700 Cascadia earthquake |
| 95229 | August 22 | Event | 1950 – Althea Gibson becomes the first black competitor in international tennis. |
| 95230 | August 22 | Event | 1952 – The penal colony on Devil's Island is permanently closed. |
| 95231 | August 22 | Event | 1961 – Ida Siekmann dies attempting to cross the Berlin Wall. |
| 95232 | August 22 | Event | 1962 – An attempt to assassinate French president Charles de Gaulle fails. |
| 95233 | August 22 | Event | 1963 – American Joe Walker in an X-15 test plane reaches an altitude of 107.96 km (67.08 mi) (354,200 feet). |
| 95234 | August 22 | Event | 1966 – Labor movements NFWA and AWOC merge to become the United Farm Workers Organizing Committee (UFWOC), predecessor of the United Farm Workers. |
| 95235 | August 22 | Event | 1968 – Pope Paul VI arrives in Bogotá, Colombia. It is the first visit of a pope to Latin America. |
| 95236 | August 22 | Event | 1971 – J. Edgar Hoover and John Mitchell announce the arrest of 20 of the Camden 28. |
| 95237 | August 22 | Event | 1972 – Rhodesia is expelled by the IOC for its racist policies. |
| 95238 | August 22 | Event | 1973 – The Congress of Chile votes in favour of a resolution condemning President Salvador Allende's government and demands him to resign or else be unseated through force and new elections be called. The first demand is executed eighteen days later in a |
| 95239 | August 22 | Event | 1978 – The Sandinista National Liberation Front (FLSN) occupies national palace in Nicaragua. |
| 95240 | August 22 | Event | 1984 – PC Brian Bishop a British police officer is shot in the head by an armed robber in Frinton-on-Sea, Essex. He dies from his injuries five days later. |
| 95241 | August 22 | Event | 1985 – Manchester Air Disaster sees 55 people killed when a fire breaks out on a commercial aircraft at Manchester Airport. |
| 95242 | August 22 | Event | 1989 – Nolan Ryan strikes out Rickey Henderson to become the first Major League Baseball pitcher to record 5,000 strikeouts. |
| 95243 | August 22 | Event | 1992 – FBI HRT sniper Lon Horiuchi shoots and kills Vicki Weaver during an 11-day siege at her home at Ruby Ridge, Idaho. |
| 95244 | August 22 | Event | 1996 – Bill Clinton signs welfare reform into law, representing major shift in US welfare policy |
| 95245 | August 22 | Event | 2003 – Alabama Chief Justice Roy Moore is suspended after refusing to comply with a federal court order to remove a rock inscribed with the Ten Commandments from the lobby of the Alabama Supreme Court building. |
| 95246 | August 22 | Event | 2004 – Versions of The Scream and Madonna, two paintings by Edvard Munch, are stolen at gunpoint from a museum in Oslo, Norway. |
| 95247 | August 22 | Event | 2006 – Pulkovo Aviation Enterprise Flight 612 crashes near the Russian border over eastern Ukraine, killing all 170 people on board. |
| 95248 | August 22 | Event | 2007 – The Texas Rangers defeat the Baltimore Orioles 30–3, the most runs scored by a team in modern Major League Baseball history. The combined run total is also Major League record. |
| 95249 | August 22 | Event | 2007 – The Storm botnet, a botnet created by the Storm Worm, sends out a record 57 million e-mails in one day |
| 95250 | August 22 | Event | 2012 – Ethnic clashes over grazing rights for cattle in Kenya's Tana River District result in more than 52 deaths. |