| 104521 | September 13 | Event | 1968 – Albania leaves the Warsaw Pact. |
| 104522 | September 13 | Event | 1971 – State police and National Guardsmen storm New York's Attica Prison to quell a prison revolt. |
| 104523 | September 13 | Event | 1971 – Chairman Mao Zedong's second in command and successor Marshal Lin Biao flees the People's Republic of China after the failure of an alleged coup. His plane crashes in Mongolia, killing all aboard. |
| 104524 | September 13 | Event | 1979 – South Africa grants independence to the "homeland" of Venda (not recognised outside South Africa). |
| 104525 | September 13 | Event | 1985 – Super Mario Bros. is released in Japan for the NES, which starts the Super Mario series of platforming games. |
| 104526 | September 13 | Event | 1987 – Goiânia accident: A radioactive object is stolen from an abandoned hospital in Goiânia, Brazil, contaminating many people in the following weeks and causing some to die from radiation poisoning. |
| 104527 | September 13 | Event | 1988 – Hurricane Gilbert is the strongest recorded hurricane in the Western Hemisphere, later replaced by Hurricane Wilma in 2005 (based on barometric pressure). |
| 104528 | September 13 | Event | 1989 – Largest anti-Apartheid march in South Africa, led by Desmond Tutu. |
| 104529 | September 13 | Event | 1993 – Israeli Prime Minister Yitzhak Rabin shakes hands with Palestine Liberation Organization chairman Yasser Arafat at the White House after signing the Oslo Accords granting limited Palestinian autonomy. |
| 104530 | September 13 | Event | 1994 – Ulysses probe passes the Sun's south pole. |
| 104531 | September 13 | Event | 2001 – Civilian aircraft traffic resumes in the United States after the September 11 attacks. |
| 104532 | September 13 | Event | 2006 – Kimveer Gill kills one student and injures 19 more in the Dawson College shooting. |
| 104533 | September 13 | Event | 2007 – The Declaration on the Rights of Indigenous Peoples is adopted by the United Nations General Assembly. |
| 104534 | September 13 | Event | 2008 – Delhi, India, is hit by a series of bomb blasts, resulting in 30 deaths and 130 injuries. |
| 104535 | September 13 | Event | 2008 – Hurricane Ike makes landfall on the Texas Gulf Coast of the United States, causing heavy damage to Galveston Island, Houston and surrounding areas. |
| 104536 | September 13 | Event | 2013 – Taliban insurgents attack the United States consulate in Herat, Afghanistan, with two members of the Afghan National Police reported dead and about 20 civilians injured. |
| 104537 | September 13 | Birth | 64 – Julia Flavia, Roman daughter of Titus (d. 91) |
| 104538 | September 13 | Birth | 678 – K'inich Ahkal Mo' Naab' III, Mayan ruler (d. 730) |
| 104539 | September 13 | Birth | 1087 – John II Komnenos, Byzantine emperor (d. 1143) |
| 104540 | September 13 | Birth | 1475 – Cesare Borgia, Italian cardinal (d. 1507) |
| 104541 | September 13 | Birth | 1502 – John Leland, English poet and historian (d. 1552) |
| 104542 | September 13 | Birth | 1521 – William Cecil, 1st Baron Burghley, English academic and politician, Lord High Treasurer (d. 1598) |
| 104543 | September 13 | Birth | 1583 – Girolamo Frescobaldi, Italian pianist and composer (d. 1643) |
| 104544 | September 13 | Birth | 1594 – Francesco Manelli, Italian theorbo player and composer (d. 1667) |
| 104545 | September 13 | Birth | 1601 – Jan Brueghel the Younger, Flemish painter (d. 1678) |
| 104546 | September 13 | Birth | 1604 – Sir William Brereton, 1st Baronet, English commander and politician (d. 1661) |
| 104547 | September 13 | Birth | 1676 – Élisabeth Charlotte d'Orléans, French wife of Leopold, Duke of Lorraine (d. 1741) |
| 104548 | September 13 | Birth | 1761 – Santō Kyōden, Japanese poet and author (d. 1816) |
| 104549 | September 13 | Birth | 1766 – Samuel Wilson, American meat-packer, namesake of Uncle Sam (d. 1854) |
| 104550 | September 13 | Birth | 1775 – Laura Secord, American-Canadian war heroine (d. 1868) |