| 107161 | September 19 | Event | 1985 – A strong earthquake kills thousands and destroys about 400 buildings in Mexico City. |
| 107162 | September 19 | Event | 1985 – Tipper Gore and other political wives form the Parents Music Resource Center as Frank Zappa and other musicians testify at U.S. Congressional hearings on obscenity in rock music. |
| 107163 | September 19 | Event | 1989 – A terrorist bomb explodes UTA Flight 772 in mid-air above the Tùnùrù Desert, Niger, killing 171. |
| 107164 | September 19 | Event | 1991 – Ötzi the Iceman is discovered by German tourists. |
| 107165 | September 19 | Event | 1995 – The Washington Post and The New York Times publish the Unabomber's manifesto. |
| 107166 | September 19 | Event | 1997 – Guelb El-Kebir massacre in Algeria where 53 people are killed. |
| 107167 | September 19 | Event | 2006 – The Thai military stages a coup in Bangkok. The Constitution is revoked and martial law is declared. |
| 107168 | September 19 | Event | 2010 – The leaking oil well in the Deepwater Horizon oil spill is sealed. |
| 107169 | September 19 | Event | 2011 – Mariano Rivera of the New York Yankees surpasses Trevor Hoffman to become Major League Baseball's all time saves leader with 602. |
| 107170 | September 19 | Birth | 86 – Antoninus Pius, Roman emperor (d. 161) |
| 107171 | September 19 | Birth | 866 – Leo VI the Wise, Byzantine emperor (d. 912) |
| 107172 | September 19 | Birth | 1328 – Joan of Kent (d. 1385) |
| 107173 | September 19 | Birth | 1377 – Albert IV, Duke of Austria (d. 1404) |
| 107174 | September 19 | Birth | 1551 – Henry III of France (d. 1589) |
| 107175 | September 19 | Birth | 1749 – Jean Baptiste Joseph Delambre, French mathematician and astronomer (d. 1822) |
| 107176 | September 19 | Birth | 1754 – John Ross Key, American lieutenant, lawyer, and judge (d. 1821) |
| 107177 | September 19 | Birth | 1759 – William Kirby, English priest and entomologist (d. 1850) |
| 107178 | September 19 | Birth | 1774 – Giuseppe Caspar Mezzofanti, Italian cardinal and linguist (d. 1849) |
| 107179 | September 19 | Birth | 1778 – Henry Brougham, 1st Baron Brougham and Vaux, Scottish lawyer and politician, Lord Chancellor of Great Britain (d. 1868) |
| 107180 | September 19 | Birth | 1796 – Hartley Coleridge, English poet and author (d. 1849) |
| 107181 | September 19 | Birth | 1802 – Lajos Kossuth, Hungarian journalist, lawyer, and politician, Governor-President of Hungary (d. 1894) |
| 107182 | September 19 | Birth | 1803 – Maria Anna of Savoy (d. 1884) |
| 107183 | September 19 | Birth | 1811 – Orson Pratt, American mathematician and religious leader (d. 1881) |
| 107184 | September 19 | Birth | 1828 – Fridolin Anderwert, Swiss judge and politician, President of the Swiss National Council (d. 1880) |
| 107185 | September 19 | Birth | 1862 – Juliusz Bursche, Polish bishop (d. 1942) |
| 107186 | September 19 | Birth | 1864 – Ragna Wettergreen, Norwegian actress (d. 1958) |
| 107187 | September 19 | Birth | 1865 – Frank Eugene, American-German photographer (d. 1936) |
| 107188 | September 19 | Birth | 1871 – Frederick Ruple, Swiss-American painter (d. 1938) |
| 107189 | September 19 | Birth | 1882 – Christopher Stone, English radio host (d. 1965) |
| 107190 | September 19 | Birth | 1883 – Mabel Vernon, American educator and activist (d. 1975) |