| 108751 | September 22 | Death | 1992 – Aurelio López, Mexican baseball player (b. 1948) |
| 108752 | September 22 | Death | 1993 – Maurice Abravanel, Greek-American pianist and conductor (b. 1903) |
| 108753 | September 22 | Death | 1994 – Leonard Feather, English-American pianist, composer, producer, and journalist (b. 1914) |
| 108754 | September 22 | Death | 1996 – Ludmilla Chiriaeff, Latvian-Canadian ballerina, choreographer, and director (b. 1924) |
| 108755 | September 22 | Death | 1996 – Dorothy Lamour, American actress and singer (b. 1914) |
| 108756 | September 22 | Death | 1999 – George C. Scott, American actor, director, and producer (b. 1927) |
| 108757 | September 22 | Death | 2000 – Saburō Sakai, Japanese lieutenant and pilot (b. 1916) |
| 108758 | September 22 | Death | 2001 – Fikret Kızılok, Turkish singer-songwriter (b. 1947) |
| 108759 | September 22 | Death | 2001 – Isaac Stern, Polish-Ukrainian violinist and conductor (b. 1920) |
| 108760 | September 22 | Death | 2002 – Jan de Hartog, Dutch-American author and playwright (b. 1914) |
| 108761 | September 22 | Death | 2003 – Gordon Jump, American actor (b. 1932) |
| 108762 | September 22 | Death | 2003 – Hugo Young, English journalist and author (b. 1938) |
| 108763 | September 22 | Death | 2004 – Big Boss Man, American wrestler (b. 1962) |
| 108764 | September 22 | Death | 2004 – Pete Schoening, American mountaineer (b. 1927) |
| 108765 | September 22 | Death | 2006 – Edward Albert, American actor and singer (b. 1951) |
| 108766 | September 22 | Death | 2006 – Carla Benschop, Dutch basketball player and educator (b. 1950) |
| 108767 | September 22 | Death | 2007 – Marcel Marceau, French mime and actor (b. 1923) |
| 108768 | September 22 | Death | 2008 – Thomas Dörflein, German zookeeper (b. 1963) |
| 108769 | September 22 | Death | 2008 – Prince Michael Andreevich of Russia (b. 1920) |
| 108770 | September 22 | Death | 2008 – Petrus Schaesberg, German painter, historian, and educator (b. 1967) |
| 108771 | September 22 | Death | 2009 – Edward Delaney, Irish sculptor (b. 1930) |
| 108772 | September 22 | Death | 2010 – Eddie Fisher, American singer and actor (b. 1928) |
| 108773 | September 22 | Death | 2010 – Vyacheslav Tsaryov, Russian footballer (b. 1971) |
| 108774 | September 22 | Death | 2011 – Cengiz Dağcı, Ukrainian-English author and poet (b. 1919) |
| 108775 | September 22 | Death | 2011 – Whatumoana Paki, New Zealand husband of Te Atairangikaahu (b. 1927) |
| 108776 | September 22 | Death | 2011 – Knut Steen, Norwegian sculptor (b. 1924) |
| 108777 | September 22 | Death | 2011 – Vesta Williams, American singer-songwriter and actress (b. 1957) |
| 108778 | September 22 | Death | 2012 – Hector Abhayavardhana, Sri Lankan theorist and academic (b. 1919) |
| 108779 | September 22 | Death | 2012 – Irving Adler, American mathematician, author, and academic (b. 1913) |
| 108780 | September 22 | Death | 2012 – Juan H. Cintrón García, Puerto Rican businessman and politician, 126th Mayor of Ponce (b. 1919) |