| 109831 | September 25 | Birth | 1954 – Sylvester Croom, American football player and coach |
| 109832 | September 25 | Birth | 1954 – Joep Lange, Dutch physician and academic (d. 2014) |
| 109833 | September 25 | Birth | 1954 – Juande Ramos, Spanish footballer and manager |
| 109834 | September 25 | Birth | 1954 – Tim Smit, Dutch-English gardener and businessman |
| 109835 | September 25 | Birth | 1955 – Ludo Coeck, Belgian footballer (d. 1985) |
| 109836 | September 25 | Birth | 1955 – Zucchero Fornaciari, Italian singer-songwriter and guitarist |
| 109837 | September 25 | Birth | 1955 – Amyr Klink, Brazilian sailor and explorer |
| 109838 | September 25 | Birth | 1955 – Luanne Rice, American author and activist |
| 109839 | September 25 | Birth | 1955 – Karl-Heinz Rummenigge, German footballer and manager |
| 109840 | September 25 | Birth | 1955 – Steven Severin, English bass player, songwriter, and producer (Siouxsie and the Banshees and The Glove) |
| 109841 | September 25 | Birth | 1956 – W. Daniel Hillis, American computer scientist, engineer, and author, founded the Thinking Machines Corporation |
| 109842 | September 25 | Birth | 1956 – Jamie Hyneman, American special effects designer and television host, founded M5 Industries |
| 109843 | September 25 | Birth | 1956 – Kim Thompson, American publisher (d. 2013) |
| 109844 | September 25 | Birth | 1957 – Michael Madsen, American actor and producer |
| 109845 | September 25 | Birth | 1957 – Vladimir Popovkin, Russian general (d. 2014) |
| 109846 | September 25 | Birth | 1957 – Ian Reddington, English actor |
| 109847 | September 25 | Birth | 1958 – Randy Kerber, American keyboard player, composer, and conductor |
| 109848 | September 25 | Birth | 1959 – Jeon Soo-il, South Korean director, producer, and screenwriter |
| 109849 | September 25 | Birth | 1960 – Igor Belanov, Ukrainian footballer and manager |
| 109850 | September 25 | Birth | 1960 – Sonia Benezra, Canadian radio and television host |
| 109851 | September 25 | Birth | 1960 – Eduardo Yáñez, Mexican actor |
| 109852 | September 25 | Birth | 1961 – Mehmet Aslantuğ, Turkish actor, director, producer, and screenwriter |
| 109853 | September 25 | Birth | 1961 – Mark Gil, Filipino actor (d. 2014) |
| 109854 | September 25 | Birth | 1961 – Heather Locklear, American actress and producer |
| 109855 | September 25 | Birth | 1962 – Shreela Ghosh, Indian-English actress and dancer |
| 109856 | September 25 | Birth | 1962 – Kalthoum Sarrai, Tunisian-French psychologist and journalist (d. 2010) |
| 109857 | September 25 | Birth | 1962 – Beth Toussaint, American actress |
| 109858 | September 25 | Birth | 1962 – Aida Turturro, American actress |
| 109859 | September 25 | Birth | 1962 – Dariusz Wdowczyk, Polish footballer and coach |
| 109860 | September 25 | Birth | 1963 – Tate Donovan, American actor and director |