| 134371 | November 27 | Event | 1868 – American Indian Wars: Battle of Washita River: United States Army Lieutenant Colonel George Armstrong Custer leads an attack on Cheyenne living on reservation land. |
| 134372 | November 27 | Event | 1886 – German judge Emil Hartwich sustains fatal injuries in a duel, which would become the background for Theodor Fontane's Effi Briest. |
| 134373 | November 27 | Event | 1895 – At the Swedish–Norwegian Club in Paris, Alfred Nobel signs his last will and testament, setting aside his estate to establish the Nobel Prize after he dies. |
| 134374 | November 27 | Event | 1901 – The U.S. Army War College is established. |
| 134375 | November 27 | Event | 1912 – Spain declares a protectorate over the north shore of Morocco. |
| 134376 | November 27 | Event | 1924 – In New York City, the first Macy's Thanksgiving Day Parade is held. |
| 134377 | November 27 | Event | 1940 – In Romania, the ruling Iron Guard fascist party assassinates over 60 of arrested King Carol II of Romania's aides and other political dissidents, including former Prime Minister Nicolae Iorga. |
| 134378 | November 27 | Event | 1940 – World War II: At the Battle of Cape Spartivento, the Royal Navy engages the Regia Marina in the Mediterranean Sea. |
| 134379 | November 27 | Event | 1942 – World War II: At Toulon, the French navy scuttles its ships and submarines to keep them out of Nazi hands. |
| 134380 | November 27 | Event | 1944 – World War II: RAF Fauld explosion: An explosion at a Royal Air Force ammunition dump in Staffordshire kills seventy people. |
| 134381 | November 27 | Event | 1945 – CARE (then the Cooperative for American Remittances to Europe) was founded to a send CARE Packages of food relief to Europe after World War II. |
| 134382 | November 27 | Event | 1954 – Alger Hiss is released from prison after serving 44 months for perjury. |
| 134383 | November 27 | Event | 1963 – The Convention on the Unification of Certain Points of Substantive Law on Patents for Invention is signed at Strasbourg. |
| 134384 | November 27 | Event | 1965 – Vietnam War: The Pentagon tells U.S. President Lyndon B. Johnson that if planned operations are to succeed, the number of American troops in Vietnam has to be increased from 120,000 to 400,000. |
| 134385 | November 27 | Event | 1968 – Penny Ann Early became the first woman to play major professional basketball, for the Kentucky Colonels in an ABA game against the Los Angeles Stars. |
| 134386 | November 27 | Event | 1971 – The Soviet space program's Mars 2 orbiter releases a descent module. It malfunctions and crashes, but it is the first man-made object to reach the surface of Mars. |
| 134387 | November 27 | Event | 1973 – Twenty-fifth Amendment: The United States Senate votes 92 to 3 to confirm Gerald Ford as Vice President of the United States. (On December 6, the House will confirm him 387 to 35). |
| 134388 | November 27 | Event | 1975 – The Provisional IRA assassinates Ross McWhirter, after a press conference in which McWhirter had announced a reward for the capture of those responsible for multiple bombings and shootings across England. |
| 134389 | November 27 | Event | 1978 – In San Francisco, city mayor George Moscone and openly gay city supervisor Harvey Milk are assassinated by former supervisor Dan White. |
| 134390 | November 27 | Event | 1978 – The Kurdistan Workers' Party (PKK) is founded in the city of Riha (Urfa) in Turkey. |
| 134391 | November 27 | Event | 1983 – Avianca Flight 011: A Boeing 747 crashes near Madrid's Barajas Airport, killing 181. |
| 134392 | November 27 | Event | 1984 – Under the Brussels Agreement signed between the governments of the United Kingdom and Spain, the former agreed to enter into discussions with Spain over Gibraltar, including sovereignty. |
| 134393 | November 27 | Event | 1987 – On a routine flight between Taiwan and Mauritius, South African Airways Flight 295 experiences an in-flight fire, apparently starting at around 23:48 on the 27th. After just under 16 minutes (leading into the early hours of November 28), the plane |
| 134394 | November 27 | Event | 1989 – Avianca Flight 203: A Boeing 727 explodes in mid-air over Colombia, killing all 107 people on board and three people on the ground. The Medellín Cartel will claim responsibility for the attack. |
| 134395 | November 27 | Event | 1991 – The United Nations Security Council adopts Security Council Resolution 721, leading the way to the establishment of peacekeeping operations in Yugoslavia. |
| 134396 | November 27 | Event | 1992 – For the second time in a year, military forces try to overthrow president Carlos Andrés Pérez in Venezuela. |
| 134397 | November 27 | Event | 1997 – Twenty-five are killed in the second Souhane massacre in Algeria. |
| 134398 | November 27 | Event | 1999 – The left-wing Labour Party takes control of the New Zealand government with leader Helen Clark becoming the first elected female Prime Minister in New Zealand's history. |
| 134399 | November 27 | Event | 2000 – In the Canadian federal election the Liberal Party of Canada wins its third consecutive election with a gain in the number of its members. |
| 134400 | November 27 | Event | 2001 – A hydrogen atmosphere is discovered on the extrasolar planet Osiris by the Hubble Space Telescope, the first atmosphere detected on an extrasolar planet. |