| 143761 | December 22 | Event | 1769 – Sino-Burmese War: The war ends with an uneasy truce. |
| 143762 | December 22 | Event | 1788 – Nguyễn Huệ proclaims himself Emperor Quang Trung, in effect abolishing on his own the Lê dynasty. |
| 143763 | December 22 | Event | 1790 – The Turkish fortress of Izmail is stormed and captured by Alexander Suvorov and his Russian armies. |
| 143764 | December 22 | Event | 1807 – The Embargo Act, forbidding trade with all foreign countries, is passed by the U.S. Congress, at the urging of President Thomas Jefferson. |
| 143765 | December 22 | Event | 1808 – Ludwig van Beethoven conducts and performs in concert at the Theater an der Wien, Vienna, with the premiere of his Fifth Symphony, Sixth Symphony, Fourth Piano Concerto (performed by Beethoven himself) and Choral Fantasy (with Beethoven at the pian |
| 143766 | December 22 | Event | 1851 – India's first freight train is operated in Roorkee, India. |
| 143767 | December 22 | Event | 1864 – Savannah, Georgia falls to General William Tecumseh Sherman, concluding his "March to the Sea". |
| 143768 | December 22 | Event | 1885 – Itō Hirobumi, a samurai, became the first Prime Minister of Japan. |
| 143769 | December 22 | Event | 1890 – Cornwallis Valley Railway begins operation between Kentville and Kingsport, Nova Scotia. |
| 143770 | December 22 | Event | 1891 – Asteroid 323 Brucia becomes the first asteroid discovered using photography. |
| 143771 | December 22 | Event | 1894 – The Dreyfus affair begins in France, when Alfred Dreyfus is wrongly convicted of treason. |
| 143772 | December 22 | Event | 1920 – The GOELRO economic development plan is adopted by the 8th Congress of Soviets of the Russian SFSR. |
| 143773 | December 22 | Event | 1937 – The Lincoln Tunnel opens to traffic in New York City. |
| 143774 | December 22 | Event | 1939 – Indian Muslims observe a "Day of Deliverance" to celebrate the resignations of members of the Indian National Congress over their not having been consulted over the decision to enter World War II with the United Kingdom. |
| 143775 | December 22 | Event | 1940 – World War II: Himarë is captured by the Greek army. |
| 143776 | December 22 | Event | 1942 – World War II: Adolf Hitler signs the order to develop the V-2 rocket as a weapon. |
| 143777 | December 22 | Event | 1944 – World War II: Battle of the Bulge – German troops demand the surrender of United States troops at Bastogne, Belgium, prompting the famous one word reply by General Anthony McAuliffe: "Nuts!" |
| 143778 | December 22 | Event | 1944 – World War II: The Vietnam People's Army is formed to resist Japanese occupation of Indochina, now Vietnam. |
| 143779 | December 22 | Event | 1947 – The Constituent Assembly of Italy approves the Constitution of Italy. |
| 143780 | December 22 | Event | 1951 – The Selangor Labour Party is founded in Selangor, Malaya. |
| 143781 | December 22 | Event | 1956 – Colo, the first gorilla to be bred in captivity, is born at the Columbus Zoo and Aquarium in Ohio. |
| 143782 | December 22 | Event | 1963 – The cruise ship Lakonia burns 180 miles (290 km) north of Madeira, Portugal with the loss of 128 lives. |
| 143783 | December 22 | Event | 1964 – The first test flight of the SR-71 (Blackbird) took place at Air Force Plant 42 in Palmdale, California. |
| 143784 | December 22 | Event | 1965 – In the United Kingdom, a 70 mph speed limit is applied to all rural roads including motorways for the first time. Previously, there had been no speed limit. |
| 143785 | December 22 | Event | 1968 – Cultural Revolution: People's Daily posted the instructions of Mao Zedong that it is "The intellectual youth must go to the country, and will be educated from living in rural poverty."(Down to the Countryside Movement) |
| 143786 | December 22 | Event | 1974 – Grande Comore, Anjouan and Mohéli vote to become the independent nation of Comoros. Mayotte remains under French administration. |
| 143787 | December 22 | Event | 1974 – The house of former British Prime Minister Edward Heath is attacked by members of the Provisional IRA. |
| 143788 | December 22 | Event | 1978 – The pivotal Third Plenum of the 11th National Congress of the Communist Party of China is held in Beijing, with Deng Xiaoping reversing Mao-era policies to pursue a program for Chinese economic reform. |
| 143789 | December 22 | Event | 1984 – Bernhard Goetz shoots four would-be muggers on an express train in Manhattan section of New York, New York. |
| 143790 | December 22 | Event | 1987 – In Zimbabwe, the political parties ZANU and ZAPU reach an agreement that ends the violence in the Matabeleland region known as the Gukurahundi. |