| 18241 | February 16 | Birth | 1497 – Philipp Melanchthon, German theologian and reformer (d. 1560) |
| 18242 | February 16 | Birth | 1519 – Gaspard II de Coligny, French admiral (d. 1572) |
| 18243 | February 16 | Birth | 1543 – Kanō Eitoku, Japanese painter and educator (d. 1590) |
| 18244 | February 16 | Birth | 1620 – Frederick William, Elector of Brandenburg (d. 1688) |
| 18245 | February 16 | Birth | 1643 – John Sharp, English archbishop (d. 1714) |
| 18246 | February 16 | Birth | 1698 – Pierre Bouguer, French mathematician, geophysicist, and astronomer (d. 1758) |
| 18247 | February 16 | Birth | 1727 – Nikolaus Joseph von Jacquin, Austrian botanist, chemist, and mycologist (d. 1817) |
| 18248 | February 16 | Birth | 1740 – Giambattista Bodoni, Italian publisher and engraver (d. 1813) |
| 18249 | February 16 | Birth | 1761 – Jean-Charles Pichegru, French general (d. 1804) |
| 18250 | February 16 | Birth | 1774 – Pierre Rode, French violinist and composer (d. 1830) |
| 18251 | February 16 | Birth | 1786 – Grand Duchess Maria Pavlovna of Russia (d. 1859) |
| 18252 | February 16 | Birth | 1802 – Phineas Quimby, American mystic and philosopher (d. 1866) |
| 18253 | February 16 | Birth | 1804 – Karl Theodor Ernst von Siebold, German physiologist and zoologist (d. 1885) |
| 18254 | February 16 | Birth | 1812 – Henry Wilson, American colonel and politician, 18th Vice President of the United States (d. 1875) |
| 18255 | February 16 | Birth | 1821 – Heinrich Barth, German explorer and scholar (d. 1865) |
| 18256 | February 16 | Birth | 1822 – Francis Galton, English biologist and statistician (d. 1911) |
| 18257 | February 16 | Birth | 1824 – Peter Kozler, Slovenian cartographer and geographer (d. 1879) |
| 18258 | February 16 | Birth | 1825 – Crosby Stuart Noyes, American newspaper publisher (d. 1908) |
| 18259 | February 16 | Birth | 1826 – Joseph Victor von Scheffel, German poet and author (d. 1886) |
| 18260 | February 16 | Birth | 1831 – Nikolai Leskov, Russian author, playwright, and journalist (d. 1895) |
| 18261 | February 16 | Birth | 1834 – Ernst Haeckel, German biologist and philosopher (d. 1919) |
| 18262 | February 16 | Birth | 1838 – Henry Adams, American journalist, historian, and author (d. 1918) |
| 18263 | February 16 | Birth | 1845 – George Kennan, American journalist and explorer (d. 1924) |
| 18264 | February 16 | Birth | 1847 – Philipp Scharwenka, Polish-German composer and educator (d. 1917) |
| 18265 | February 16 | Birth | 1848 – Hugo de Vries, Dutch botanist, geneticist, and academic (d. 1935) |
| 18266 | February 16 | Birth | 1848 – Octave Mirbeau, French journalist, author, and playwright (d. 1917) |
| 18267 | February 16 | Birth | 1856 – Willem Kes, Dutch violinist and conductor (d. 1934) |
| 18268 | February 16 | Birth | 1856 – Ossian Everett Mills, American academic, founded Phi Mu Alpha Sinfonia (d. 1920) |
| 18269 | February 16 | Birth | 1866 – Billy Hamilton, American baseball player and manager (d. 1940) |
| 18270 | February 16 | Birth | 1873 – Radoje Domanović, Serbian satirist and journalist (d. 1908) |