| 20281 | February 22 | Event | 1995 – The Corona reconnaissance satellite program, in existence from 1959 to 1972, is declassified. |
| 20282 | February 22 | Event | 1997 – In Roslin, Scotland, scientists announce that an adult sheep named Dolly has been successfully cloned. |
| 20283 | February 22 | Event | 2002 – Angolan political and rebel leader Jonas Savimbi is killed in a military ambush. |
| 20284 | February 22 | Event | 2006 – At least six men stage Britain's biggest robbery, stealing £53m (about $92.5 million or €78 million) from a Securitas depot in Tonbridge, Kent. |
| 20285 | February 22 | Event | 2011 – New Zealand's second deadliest earthquake strikes Christchurch, killing 185 people. |
| 20286 | February 22 | Event | 2011 – Bahraini uprising: Tens of thousands of people march in protest against the deaths of seven victims killed by police and army forces during previous protests. |
| 20287 | February 22 | Event | 2012 – A train crash in Buenos Aires, Argentina, kills 51 people and injures 700 others. |
| 20288 | February 22 | Event | 2014 – President Viktor Yanukovych of Ukraine is impeached by the Verkhovna Rada of Ukraine by a vote of 328-0, fulfilling a major goal of the Euromaidan rebellion. |
| 20289 | February 22 | Event | 2015 – A ferry carrying 100 passengers capsizes in the Padma River, killing 70 people. |
| 20290 | February 22 | Birth | 1040 – Rashi, French rabbi and author (d. 1105) |
| 20291 | February 22 | Birth | 1403 – Charles VII of France (d. 1461) |
| 20292 | February 22 | Birth | 1440 – Ladislaus the Posthumous, Hungarian king (d. 1457) |
| 20293 | February 22 | Birth | 1500 – Rodolfo Pio da Carpi, Italian cardinal (d. 1564) |
| 20294 | February 22 | Birth | 1514 – Tahmasp I, Iranian ruler (d. 1576) |
| 20295 | February 22 | Birth | 1645 – Johann Ambrosius Bach, German violinist and composer (d. 1695) |
| 20296 | February 22 | Birth | 1645 – Johann Christoph Bach, German pianist and composer (d. 1693) |
| 20297 | February 22 | Birth | 1705 – Peter Artedi, Swedish ichthyologist and zoologist (d. 1735) |
| 20298 | February 22 | Birth | 1732 – George Washington, American general and politician, 1st President of the United States (d. 1799) |
| 20299 | February 22 | Birth | 1749 – Johann Nikolaus Forkel, German musician and musicologist (d. 1818) |
| 20300 | February 22 | Birth | 1756 – Georg Friedrich von Martens, German jurist and diplomat (d. 1821) |
| 20301 | February 22 | Birth | 1761 – Erik Tulindberg, Finnish violinist and composer (d. 1814) |
| 20302 | February 22 | Birth | 1778 – Rembrandt Peale, American painter and curator (d. 1860) |
| 20303 | February 22 | Birth | 1779 – Joachim Nicolas Eggert, Swedish composer and musical director (d. 1813) |
| 20304 | February 22 | Birth | 1788 – Arthur Schopenhauer, German philosopher and author (d. 1860) |
| 20305 | February 22 | Birth | 1796 – Alexis Bachelot, French priest and missionary (d. 1837) |
| 20306 | February 22 | Birth | 1796 – Adolphe Quetelet, Belgian mathematician, astronomer, and sociologist (d. 1874) |
| 20307 | February 22 | Birth | 1806 – Józef Kremer, Polish historian and philosopher (d. 1875) |
| 20308 | February 22 | Birth | 1810 – Frédéric Chopin, Polish pianist and composer (d. 1849) |
| 20309 | February 22 | Birth | 1817 – Carl Wilhelm Borchardt, German mathematician and academic (d. 1880) |
| 20310 | February 22 | Birth | 1819 – James Russell Lowell, American poet and critic (d. 1891) |