| 21271 | February 25 | Event | 1836 – Samuel Colt is granted a United States patent for the Colt revolver. |
| 21272 | February 25 | Event | 1843 – Lord George Paulet occupies the Kingdom of Hawaii in the name of Great Britain in the Paulet Affair (1843). |
| 21273 | February 25 | Event | 1848 – Provisional government in revolutionary France, by Louis Blanc's motion, guarantees workers' rights. |
| 21274 | February 25 | Event | 1856 – A Peace conference opens in Paris after the Crimean War. |
| 21275 | February 25 | Event | 1866 – Miners in Calaveras County, California, discover what is now called the Calaveras Skull - human remains that supposedly indicated that man, mastodons, and elephants had co-existed. |
| 21276 | February 25 | Event | 1870 – Hiram Rhodes Revels, a Republican from Mississippi, is sworn into the United States Senate, becoming the first African American ever to sit in the U.S. Congress. |
| 21277 | February 25 | Event | 1875 – Guangxu Emperor of Qing dynasty China begins his reign, under Empress Dowager Cixi's regency. |
| 21278 | February 25 | Event | 1901 – J. P. Morgan incorporates the United States Steel Corporation. |
| 21279 | February 25 | Event | 1912 – Marie-Adélaïde, the eldest of six daughters of Guillaume IV, becomes the first reigning Grand Duchess of Luxembourg. |
| 21280 | February 25 | Event | 1916 – World War I: The Germans capture Fort Douaumont during the Battle of Verdun. |
| 21281 | February 25 | Event | 1919 – Oregon places a one cent per U.S. gallon tax on gasoline, becoming the first U.S. state to levy a gasoline tax. |
| 21282 | February 25 | Event | 1921 – Tbilisi, capital of the Democratic Republic of Georgia, is occupied by Bolshevist Russia. |
| 21283 | February 25 | Event | 1928 – Charles Jenkins Laboratories of Washington, D.C. becomes the first holder of a broadcast license for television from the Federal Radio Commission. |
| 21284 | February 25 | Event | 1932 – Adolf Hitler obtains German citizenship by naturalization, which allows him to run in the 1932 election for Reichspräsident. |
| 21285 | February 25 | Event | 1933 – The USS Ranger is launched. It is the first US Navy ship to be built solely as an aircraft carrier. |
| 21286 | February 25 | Event | 1941 – February strike: In occupied Amsterdam, a general strike is declared in response to increasing anti-Jewish measures instituted by the Nazis. |
| 21287 | February 25 | Event | 1945 – World War II: Turkey declares war on Germany. |
| 21288 | February 25 | Event | 1947 – The State of Prussia ceases to exist. |
| 21289 | February 25 | Event | 1948 – The Communist Party takes control of government in Czechoslovakia and the period of the Third Republic ends. |
| 21290 | February 25 | Event | 1951 – The first Pan American Games are held in Buenos Aires, Argentina. |
| 21291 | February 25 | Event | 1954 – Gamal Abdel Nasser is made premier of Egypt. |
| 21292 | February 25 | Event | 1956 – In his speech On the Cult of Personality and Its Consequences, Nikita Khrushchev, leader of the Soviet Union denounces the cult of personality of Joseph Stalin. |
| 21293 | February 25 | Event | 1964 – North Korean Prime Minister Kim Il-sung calls for the removal of feudalistic land ownership aimed at turning all cooperative farms into state-run ones. |
| 21294 | February 25 | Event | 1964 – U.S. Air Force launches a satellite employing a US Air Force Atlas/Agena combination from Point Arguello (LC-2-3) in California and from Cape Kennedy in Florida. |
| 21295 | February 25 | Event | 1968 – Vietnam War: One hundred thirty-five unarmed citizens of Hà My village in South Vietnam's Quảng Nam Province are killed and buried en masse by South Korean troops in what would come to be known as the Hà My massacre. |
| 21296 | February 25 | Event | 1971 – The first unit of the Pickering Nuclear Generating Station, the first commercial nuclear power station in Canada, goes online. |
| 21297 | February 25 | Event | 1980 – The government of Suriname is overthrown by a military coup led by Dési Bouterse. |
| 21298 | February 25 | Event | 1986 – People Power Revolution: President of the Philippines Ferdinand Marcos flees the nation after 20 years of rule Corazon Aquino becomes the Philippines' first woman president. |
| 21299 | February 25 | Event | 1987 – Southern Methodist University's football program is the first college football program to receive the death penalty by the NCAA's Committee on Infractions. It was revealed that athletic officials and school administrators had knowledge of a "slush |
| 21300 | February 25 | Event | 1991 – Gulf War: An Iraqi scud missile hits an American military barracks in Dhahran, Saudi Arabia killing 28 U.S. Army Reservists from Pennsylvania. |