| 21601 | February 25 | Death | 1715 – Pu Songling, Chinese author (b. 1640) |
| 21602 | February 25 | Death | 1723 – Christopher Wren, English architect, designed St Paul's Cathedral (b. 1632) |
| 21603 | February 25 | Death | 1756 – Eliza Haywood, English actress and poet (b. 1693) |
| 21604 | February 25 | Death | 1796 – Samuel Seabury, American bishop (b. 1729) |
| 21605 | February 25 | Death | 1798 – Louis Jules Mancini Mazarini, French poet and diplomat (b. 1716) |
| 21606 | February 25 | Death | 1805 – Thomas Pownall, English politician, Governor of the Province of Massachusetts Bay (b. 1722) |
| 21607 | February 25 | Death | 1815 – Stanoje Glavaš, Serbian soldier (b. 1763) |
| 21608 | February 25 | Death | 1819 – Francisco Manoel de Nascimento, Portuguese-French poet and educator (b. 1734) |
| 21609 | February 25 | Death | 1822 – William Pinkney, American politician and diplomat, 7th United States Attorney General (b. 1764) |
| 21610 | February 25 | Death | 1831 – Friedrich Maximilian Klinger, German author and playwright (b. 1752) |
| 21611 | February 25 | Death | 1841 – Philip Pendleton Barbour, American lawyer, judge, and politician, 12th Speaker of the United States House of Representatives (b. 1783) |
| 21612 | February 25 | Death | 1850 – Daoguang Emperor of China (b. 1782) |
| 21613 | February 25 | Death | 1852 – Thomas Moore, Irish-English singer-songwriter and poet (b. 1779) |
| 21614 | February 25 | Death | 1860 – Chauncey Allen Goodrich, American clergyman, lexicographer, and educator (b. 1790) |
| 21615 | February 25 | Death | 1864 – Anna Harrison, American wife of William Henry Harrison, 9th First Lady of the United States (b. 1775) |
| 21616 | February 25 | Death | 1865 – Otto Ludwig, German author, playwright, and critic (b. 1813) |
| 21617 | February 25 | Death | 1870 – Henrik Hertz, Danish poet and playwright (b. 1797) |
| 21618 | February 25 | Death | 1877 – Jung Bahadur Rana, Nepalese ruler (b. 1816) |
| 21619 | February 25 | Death | 1878 – Townsend Harris, American merchant, politician, and diplomat, United States Ambassador to Japan (b. 1804) |
| 21620 | February 25 | Death | 1888 – Josif Pančić, Croatian-Serbian botanist and academic (b. 1814) |
| 21621 | February 25 | Death | 1894 – Steele MacKaye, American actor and playwright (b. 1842) |
| 21622 | February 25 | Death | 1899 – Paul Reuter, German-English journalist (b. 1816) |
| 21623 | February 25 | Death | 1906 – Anton Arensky, Russian pianist and composer (b. 1861) |
| 21624 | February 25 | Death | 1910 – Worthington Whittredge, American painter and educator (b. 1820) |
| 21625 | February 25 | Death | 1911 – Friedrich Spielhagen, German author, theorist, and translator (b. 1829) |
| 21626 | February 25 | Death | 1912 – William IV, Grand Duke of Luxembourg (b. 1852) |
| 21627 | February 25 | Death | 1914 – John Tenniel, English illustrator (b. 1820) |
| 21628 | February 25 | Death | 1915 – Charles Edwin Bessey, American botanist, author, and academic (b. 1845) |
| 21629 | February 25 | Death | 1916 – David Bowman, Australian politician (b. 1860) |
| 21630 | February 25 | Death | 1919 – Josef Christiaens, Belgian race car driver and engineer (b. 1879) |