| 21631 | February 25 | Death | 1920 – Marcel-Auguste Dieulafoy, French archaeologist and engineer (b. 1844) |
| 21632 | February 25 | Death | 1922 – Henri Désiré Landru, French serial killer (b. 1869) |
| 21633 | February 25 | Death | 1928 – William O'Brien, Irish journalist and politician (b. 1852) |
| 21634 | February 25 | Death | 1934 – Elizabeth Gertrude Britton, American botanist and academic (b. 1857) |
| 21635 | February 25 | Death | 1934 – John McGraw, American baseball player and manager (b. 1873) |
| 21636 | February 25 | Death | 1940 – Mary Mills Patrick, American author and academic (b. 1850) |
| 21637 | February 25 | Death | 1945 – Mário de Andrade, Brazilian author, poet, and photographer (b. 1893) |
| 21638 | February 25 | Death | 1946 – René Le Grèves, French cyclist (b. 1910) |
| 21639 | February 25 | Death | 1950 – George Minot, American physician and academic, Nobel Prize laureate (b. 1885) |
| 21640 | February 25 | Death | 1953 – Sergei Winogradsky, Ukrainian-Russian microbiologist and ecologist (b. 1856) |
| 21641 | February 25 | Death | 1954 – Auguste Perret, French architect, designed the Théâtre des Champs-Élysées (b. 1874) |
| 21642 | February 25 | Death | 1957 – Mark Aldanov, Russian author and critic (b. 1888) |
| 21643 | February 25 | Death | 1957 – Bugs Moran, American gangster (b. 1893) |
| 21644 | February 25 | Death | 1963 – Melville J. Herskovits, American anthropologist and academic (b. 1895) |
| 21645 | February 25 | Death | 1964 – Alexander Archipenko, Ukrainian sculptor and illustrator (b. 1887) |
| 21646 | February 25 | Death | 1964 – Maurice Farman, French race car driver and pilot (b. 1877) |
| 21647 | February 25 | Death | 1964 – Hinrich Lohse, German politician (b. 1896) |
| 21648 | February 25 | Death | 1964 – Grace Metalious, American author (b. 1924) |
| 21649 | February 25 | Death | 1964 – Kenneth Lee Spencer, American actor and singer (b. 1913) |
| 21650 | February 25 | Death | 1965 – Philip Babington, English Air Marshal (b. 1894) |
| 21651 | February 25 | Death | 1966 – James D. Norris, American businessman (b. 1906) |
| 21652 | February 25 | Death | 1970 – Mark Rothko, Latvian-American painter and academic (b. 1903) |
| 21653 | February 25 | Death | 1971 – Theodor Svedberg, Swedish chemist and academic, Nobel Prize laureate (b. 1884) |
| 21654 | February 25 | Death | 1975 – Elijah Muhammad, American religious leader (b. 1897) |
| 21655 | February 25 | Death | 1975 – Georg Olden, African-American graphic designer (b. 1920) |
| 21656 | February 25 | Death | 1978 – Daniel James, Jr., American general and pilot (b. 1920) |
| 21657 | February 25 | Death | 1980 – Robert Hayden, American poet and academic (b. 1913) |
| 21658 | February 25 | Death | 1983 – Tennessee Williams, American playwright and author (b. 1911) |
| 21659 | February 25 | Death | 1983 – John Cowles, Sr., American publisher, founded the Cowles Media Company (b. 1898) |
| 21660 | February 25 | Death | 1987 – James Coco, American actor and singer (b. 1930) |