| 22141 | February 27 | Birth | 1667 – Ludwika Karolina Radziwiłł, Prussian-Lithuanian wife of Charles III Philip, Elector Palatine (d. 1695) |
| 22142 | February 27 | Birth | 1689 – Pietro Gnocchi, Italian composer, director, historian, and geographer (d. 1775) |
| 22143 | February 27 | Birth | 1691 – Edward Cave, English publisher, founded The Gentleman's Magazine (d. 1754) |
| 22144 | February 27 | Birth | 1711 – Constantine Mavrocordatos, Ottoman ruler (d. 1769) |
| 22145 | February 27 | Birth | 1724 – Frederick Michael, Count Palatine of Zweibrücken (d. 1767) |
| 22146 | February 27 | Birth | 1732 – Jean de Dieu-Raymond de Cucé de Boisgelin, French cardinal (d. 1804) |
| 22147 | February 27 | Birth | 1746 – Louis-Jérôme Gohier, French politician, French Minister of Justice (d. 1830) |
| 22148 | February 27 | Birth | 1748 – Anders Erikson Sparrman, Swedish physician and activist (d. 1820) |
| 22149 | February 27 | Birth | 1767 – Jacques-Charles Dupont de l'Eure, French lawyer and politician, 24th Prime Minister of France (d. 1855) |
| 22150 | February 27 | Birth | 1779 – Thomas Hazlehurst, English businessman, founded Hazlehurst & Sons (d. 1842) |
| 22151 | February 27 | Birth | 1789 – Manuel Rodríguez Erdoíza, Chilean lawyer and politician, Chilean Minister of National Defense (d. 1818) |
| 22152 | February 27 | Birth | 1795 – José Antonio Navarro, American merchant and politician (d. 1871) |
| 22153 | February 27 | Birth | 1807 – Henry Wadsworth Longfellow, American poet and educator (d. 1882) |
| 22154 | February 27 | Birth | 1809 – Jean-Charles Cornay, French missionary and saint (d. 1837) |
| 22155 | February 27 | Birth | 1812 – Pieter Harting, Dutch biologist and botanist (d. 1885) |
| 22156 | February 27 | Birth | 1831 – Nikolai Ge, Russian painter (d. 1894) |
| 22157 | February 27 | Birth | 1846 – Franz Mehring, German historian and politician (d. 1919) |
| 22158 | February 27 | Birth | 1847 – Ellen Terry, English actress (d. 1928) |
| 22159 | February 27 | Birth | 1848 – Hubert Parry, English composer and historian (d. 1918) |
| 22160 | February 27 | Birth | 1850 – Laura E. Richards, American author and poet (d. 1943) |
| 22161 | February 27 | Birth | 1856 – Mattia Battistini, Italian opera singer (d. 1928) |
| 22162 | February 27 | Birth | 1859 – Bertha Pappenheim, Austrian-German activist and author (d. 1936) |
| 22163 | February 27 | Birth | 1862 – Anastasios Metaxas, Greek target shooter and architect (d. 1937) |
| 22164 | February 27 | Birth | 1863 – Joaquín Sorolla, Spanish painter (d. 1923) |
| 22165 | February 27 | Birth | 1863 – George Herbert Mead, American sociologist and philosopher (d. 1930) |
| 22166 | February 27 | Birth | 1864 – Eemil Nestor Setälä, Finnish linguist and politician, Finnish Minister for Foreign Affairs (d. 1935) |
| 22167 | February 27 | Birth | 1867 – Irving Fisher, American economist and statistician (d. 1947) |
| 22168 | February 27 | Birth | 1867 – Wilhelm Peterson-Berger, Swedish composer and critic (d. 1942) |
| 22169 | February 27 | Birth | 1869 – Alice Hamilton, American physician and academic (d. 1970) |
| 22170 | February 27 | Birth | 1870 – Louis Coerne, American composer and educator (d. 1922) |