| 25261 | March 6 | Event | 1902 – Real Madrid C.F. is founded. |
| 25262 | March 6 | Event | 1912 – Italian forces become the first to use airships in war, as two dirigibles drop bombs on Turkish troops encamped at Janzur, from an altitude of 6,000 feet. |
| 25263 | March 6 | Event | 1921 – Portuguese Communist Party is founded as the Portuguese Section of the Communist International. |
| 25264 | March 6 | Event | 1930 – International Unemployment Day demonstrations globally initiated by the Comintern |
| 25265 | March 6 | Event | 1943 – Norman Rockwell published Freedom from Want in the The Saturday Evening Post with a matching essay by Carlos Bulosan as part of the Four Freedoms series. |
| 25266 | March 6 | Event | 1945 – World War II: Cologne is captured by American Troops. |
| 25267 | March 6 | Event | 1946 – Ho Chi Minh signs an agreement with France which recognizes Vietnam as an autonomous state in the Indochinese Federation and the French Union. |
| 25268 | March 6 | Event | 1951 – The trial of Ethel and Julius Rosenberg begins. |
| 25269 | March 6 | Event | 1953 – Georgy Malenkov succeeds Joseph Stalin as Premier of the Soviet Union and First Secretary of the Communist Party of the Soviet Union. |
| 25270 | March 6 | Event | 1957 – Ghana becomes the first Sub-Saharan country to gain independence from the British |
| 25271 | March 6 | Event | 1962 – Ash Wednesday Storm of 1962 begins on the mid-Atlantic coast of the United States. |
| 25272 | March 6 | Event | 1964 – Nation of Islam leader Elijah Muhammad officially gives boxing champion Cassius Clay the name Muhammad Ali. |
| 25273 | March 6 | Event | 1964 – Constantine II becomes King of Greece. |
| 25274 | March 6 | Event | 1965 – Premier Tom Playford of South Australia loses power after 27 years in office. |
| 25275 | March 6 | Event | 1967 – Joseph Stalin's daughter Svetlana Alliluyeva defects to the United States. |
| 25276 | March 6 | Event | 1968 – The first of the East L.A. walkouts take place at several high schools. |
| 25277 | March 6 | Event | 1968 – Three rebels are executed by Rhodesia, the first executions since UDI, prompting international condemnation. |
| 25278 | March 6 | Event | 1970 – An explosion at the Weather Underground safe house in Greenwich Village kills three. |
| 25279 | March 6 | Event | 1975 – For the first time the Zapruder film of the assassination of John F. Kennedy is shown in motion to a national TV audience by Robert J. Groden and Dick Gregory. |
| 25280 | March 6 | Event | 1975 – Algiers Accord: Iran and Iraq announce a settlement of their border dispute. |
| 25281 | March 6 | Event | 1981 – After 19 years of presenting the CBS Evening News, Walter Cronkite signs off for the last time. |
| 25282 | March 6 | Event | 1983 – The first United States Football League game is played. |
| 25283 | March 6 | Event | 1987 – The British ferry MS Herald of Free Enterprise capsizes in about 90 seconds killing 193. |
| 25284 | March 6 | Event | 1988 – Three Provisional Irish Republican Army volunteers are killed by Special Air Service on the territory of Gibraltar in the conclusion of Operation Flavius. |
| 25285 | March 6 | Event | 1990 – Ed Yielding and Joseph T. Vida set the transcontinental speed record flying a SR-71 Blackbird from Los Angeles to Virginia in 64 minutes, averaging 2,124 mph. |
| 25286 | March 6 | Event | 1992 – The Michelangelo computer virus begins to affect computers. |
| 25287 | March 6 | Event | 2008 – A suicide bomber kills 68 people (including first responders) in Baghdad on the same day that a gunman kills eight students in Jerusalem. |
| 25288 | March 6 | Birth | 1340 – John of Gaunt, 1st Duke of Lancaster, Belgian-English politician, Lord High Steward of Great Britain (d. 1399) |
| 25289 | March 6 | Birth | 1405 – John II of Castile (d. 1454) |
| 25290 | March 6 | Birth | 1459 – Jakob Fugger, German merchant and banker (d. 1525) |